摘要
目的 探讨抑郁、焦虑障碍对癌症病人生活质量的影响。方法 采用癌症病人生活质量问巷(EORCTQLQ-30)、艾森克人格问卷(EPQ)、防御方式问卷(DSQ)、生活事件量表(LES)、社会支持评定量表(SSRS),入院1周内对1244例癌症患者进行测查,采用汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HAMA)评定病人的情绪.测查结果用t检验,多元逐步回归进行统计分析,结果 抑郁组(40例)躯体功能(7.69±0.24)分、角色功能(3.03±0.11)分、社会功能(5.74±0.17)分、情感功能(7.59±0.31)分、认知功能(3.59±017)分、生活质量总评(7.26±0.41)分、睡眠(2.20±0.13)分、食欲(1.79±0.11)分、疼痛(3.79±0.27)分、便秘(1.31±0.11)分与无抑郁组(84例)比较有显著差异;与无焦虑组(87例)比较,焦虑组(37例)认知功能(3.53±0.19)分、情感功能(8.28±0.27)分、乏力(7.34±0.31)分、疼痛(4.00±0.30)分、睡眠(2.16±0.14)分、食欲(1.78±0.12)分、便秘(1.41±0.14)分、腹泻(1.13±7.45)分、呼吸(1.56±0.13)分及生活质量总评(7.31±0.44)分等方面有显著性差异。多元分析结果表明,癌症患者生活质量总评与负性生活事件强度、疼痛、疲劳、社会支持利用度有关,社会功能与年龄、疲劳、HMAD总分有关。结论 抑郁、焦虑等情绪障碍严重影响了病人的生活质量,负性生活事件、神经质个性、年龄、病程也影响患者生活质量。
Objective To study on emotional disorder ,which affect cancer patients' quality of life .Methods 124 patients who accepted radiotherapy were estimated by EORCT QLQ-30, EPQ, DSQ, LES, SRS within a week of pretherapy. Using Hamilton depression scale and Hamilton anxiety scale evaluated cancer patients' emotion. The result was analyzed by t -cheek and multielement stepwise regression .Results The patients with depression (40)whose body function ( 7.69 ± 0.24 ), role function ( 3.03 ± 0.11 ), social function ( 5.74 ± 0.17 ), sentiment funcion ( 7.59 ± 0.31 ), cognition ( 3.59 ± 0.17 ), general comment of quality of life ( 7.26 ± 0.41 ), sleep( 2.20 ± 0.13 ), appetite ( 1.79 ± 0.11 ), pain( 3.79±0.27 ), oppilation ( 1.31 ± 0.11 )were significant difference than cancer patients with no depression ( 84 ); To compare with no anxious cancer patients ( 87 ), anxious patients ( 37 ) whose congtioni ( 3.53 ±0.19 ), affection( 8.28 ± 0.27 )., fatigue( 7.34 ± 0.31 ), pain( 4.00 ± 0.30 ), sleep( 2.16 ± 0.14 ), appetite( 1.78±0.12 ), oppilation( 1.41 ± 0.14 ), diarrhea ( 1.13 ± 7.45 ), breath ( 1.56±0.13 ) and general comment of quality of life (7.31 ±0.44 ) had significant difference, In multivariate analysis, the quality of life was related to negative life events, pain, fatigue and social support; the social function was related to age, fatigue and score of HAMD. Conclusion Depression and anxiety influence cancer patients'quality of life .Negative life events, nervousness, age, course of disease influence cancer patients' quality of life.
出处
《中华临床医学杂志》
2006年第3期9-12,共4页
Chinese Journal of Clinical Practical Medicine
关键词
生活质量
抑郁
焦虑
癌症
Quality of life Depression Anxiety