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镉对黑斑蛙脏器组织的亚慢性毒性效应 被引量:5

Subchronic toxic effects of cadmium on the viscera tissues of the frog Rana nigromaculata
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摘要 研究了在不同浓度镉(10-40mg/L)中暴露30d 黑斑蛙(Rana nigromaculata)脏器组织的亚慢性毒性效应.结果表明,当镉暴露浓度〉30mg/L时,黑斑蛙的肝脏指数显著减少.黑斑蛙肝脏、肾脏和心脏Na^+-K^+-ATPase活性随着Cd^2+浓度的升高而降低,表现出明显的浓度-效应关系.在同一浓度(20mg/L)不同时间处理中,肝脏、肾脏组织Na^+-K^+-ATPase活性随处理时间的延长表现为先升高后下降的趋势.肝脏和肾脏Na^+-K^+-ATPase对Cd^2+更为敏感.肝脏指数的减少和肝脏、肾脏、心脏组织Na^+-K^+-ATPase活性的变化在一定程度上反映了镉对黑斑蛙的损伤作用. The subchronic toxic effects of Rana nigromaculata viscera tissues exposed 30d in different Cd^2+ concentrations (10-40mg/L) were studied adopting toxial experiment technique. At the exposure concentration 〉30mg/L, the hepatosomatic index (HSI) of Rana nigromaculata decreased markedly. The Na^+-K^+-ATPase activities in the liver, kidney and heart decreased with Cd^2+ concentration increased, expressing obvious concentration-effect relationship. In the treatment of same concentration (20mg/L) and different time, the Na^+-K^+-ATPase activities in the liver and kidney tissues tended to raise first and then declined, and there two tissues showed more sensitive on Cd^2+. The decrease of HSI and the change of Na^+-K^+-ATPase activities of liver, kidney and heart reflected at definite degree the damage action of cadmium on Rana nigromaculata.
出处 《中国环境科学》 EI CAS CSCD 北大核心 2006年第2期228-232,共5页 China Environmental Science
基金 浙江省自然科学基金资助项目(302056) 浙江省动物学重点学科资助项目
关键词 黑斑蛙 肝脏指数 Na^+-K^+-ATPase活性 毒性效应 cadmium Rana nigromaculata hepatosomatic index Na^+-K^+-ATPase activities toxic effect
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