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The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine

The Effect of Potassium Citrate on Simultaneous Growth of Calcium Oxalate Mono-, Di-, and Trihydrate in Synthetic Urine
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摘要 The inducing effect of potassium citrate (K3cit) on simultaneous growth of calcium oxalate mono-(COM), di-(COD), and trihydrate (COT) crystals in synthetic urine was observed with double diffusion gelatinous technique. K3cit can induce the formation of COD and COT, inhibit the aggregation and decrease the surface area of COM crystals. It supported the clinical use of K3cit and may provide important clues to this disease in cure and in search for new drugs. The inducing effect of potassium citrate (K3cit) on simultaneous growth of calcium oxalate mono-(COM), di-(COD), and trihydrate (COT) crystals in synthetic urine was observed with double diffusion gelatinous technique. K3cit can induce the formation of COD and COT, inhibit the aggregation and decrease the surface area of COM crystals. It supported the clinical use of K3cit and may provide important clues to this disease in cure and in search for new drugs.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2006年第5期687-690,共4页 中国化学快报(英文版)
基金 This research work was granted by the National Natural Science Foundation of China (No 20471024).
关键词 Calcium oxalate potassium citrate BIOMINERALIZATION urinary stone gel. Calcium oxalate, potassium citrate, biomineralization, urinary stone, gel.
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参考文献1

  • 1P. O. Schwille,U. Herrmann,C. Wolf,I. Berger,R. Meister.Citrate and recurrent idiopathic calcium urolithiasis[J].Urological Research.1992(2)

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