摘要
目的观察源于日本的门诊森田心理治疗对强迫症的疗效,探讨其在强迫症治疗中的作用。方法将符合CCMD-3诊断标准的67例强迫症患者随机分为两组,A组(研究组)为门诊森田治疗合并5-羟色胺再摄取抑制剂(SSRIs)治疗;B组(对照组)为单纯药物治疗。进行12周的动态观察,之后每月随访1次,共随访6个月。应用Yale-Brown强迫症状量表(Y-BOCS)、Hamilton焦虑量表(HAMA)和临床疗效总评量表(CGI-GI)于治疗前及治疗后第2、4、8、12周末及6个月后进行测评。以Y-BOCS减分率评定其有效率。结果在第4周末时,两组疗效近似差异无统计学意义(P>0.05),治疗8周后研究组Y-BOCS、HAMA、CGI-GI评分下降较对照组明显,差异有统计学意义(P<0.05)。疗程12周末,A组患者较对照组Y-BOCS、HAMA、CGI-GI评分下降更明显,差异有统计学意义(P<0.01)。6个月后随访,研究组与对照组临床有效率分别为86.67%、63.33%,研究组长期疗效优于对照组,差异有统计学意义(P<0.05)。结论门诊森田治疗结合SSRIs药物是治疗强迫症的较好方法。
Objective To investigate the efficacy of clinic Morita therapy in the treatment of obsessive-compulsive disorder （OCD）. Methods Sixty patients who met the Chinese Classification and Diagnostic Criteria for Mental Disorders, the Third Edition（CCMD-3） for OCD were involved during the twelve weeks study. All patients were randomly divided into two treatment groups, group A（treated with combination of clinic Morita therapy and drug）and group B（treated only with SSRIs）. All of them were evaluated with Yale-Brown Obsessive- Compulsive Scale（Y-BOCS） and Hamilton Anxiety Rating Scale（HAMA） before treatment and at the end of 2nd,4th,8th, 12th weeks and sixth month during treatment Clinic Morita therapy and SSRIs efficacy in the treatment of OCD were assessed with percentage decrease on the Y-BOCS and CGI. Results After four weeks the therapeutic efficacy in group A was similar to that in group B（P〈0.05）. After eight weeks the scores of Y-BOCS, HAMA,CGI-GI in group A was significantly lower than that in group B（P〈0.05 or P〈0.01）. At the end of treatment （six months） the efficacy rate of group A and group B was respectively 86.67 %, 63. 33 % （P〈0. 05）. There were more better long-time efficacy in group A （P〈 0.01 ）. Conclusion Combining with clinic Morita therapy and SSRIs is optimal for OCD.
出处
《重庆医学》
CAS
CSCD
2006年第9期828-830,共3页
Chongqing medicine
关键词
强迫症
门诊森田治疗
SSRIS
疗效
obsessive-compulsive disorder
clinic Morita therapy
SSRIs
efficacy
