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新生儿念珠菌血症流行病学及易患因素研究进展 被引量:10

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摘要 念珠菌是新生儿重症监护室(NICU)重要的病原体,它可通过感染播散引起脑膜炎,肾脏、脾或肝脓肿,眼内炎,骨髓炎及侵袭性皮肤炎,而血液感染是最常见形式。念珠菌血症的发生率逐年上升,尤其在NICU,占院内感染性疾病的15.8%。由于早产儿和低体重儿自身的内在特点,如T淋巴细胞数量的减少,中性粒细胞数量及功能的降低,皮肤结构的不成熟,表皮屏障的破裂等导致其相应的免疫功能低下,更容易发生侵袭性真菌感染。
作者 胡娅 余加林
出处 《中国新生儿科杂志》 CAS 2006年第2期115-117,共3页 Chinese Journal of Neonatology
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