摘要
目的探讨新生儿缺氧缺血性脑病胆红素的变化以及经皮测胆的准确性。方法用抽血以及经皮测胆两种方法对59例确诊为缺氧缺血性脑病的新生儿于出生第2天及第5天进行胆红素测定,并将两种方法测定结果进行比较。结果出生第2天各组间胆红素值无显著性差异,出生第5天胆红素值随着缺氧缺血性脑病程度加重明显降低,且有显著性差异(P<0.05)。经皮测胆红素值轻度175.78±45.39;中度137.02±46.24;重度95.58±42.62。抽血测胆以及经皮测胆两种方法测得结果进行比较无显著性差异(P>0.05)。结论在出生第5天中重度缺氧缺血性脑病患儿胆红素值明显低于轻度组,各组间比较有显著性差异。经皮测胆是一种准确经济的测定胆红素方法。
Objective To investigate changes in serum bilirubin levels of the neonates with HIE and accuracy of percutaneous bilirubin detection. Methods Bilirubin levels of 59 neonates with HIE in the blood and in the skin were detected and the results determined by the two methods were compared at the 2th day, the 5th day after birth, respectively. Resulds In bilirubin level, there was no significant difference among the groups at the 2th day after birth. At the 5th day, the bilirubin level significantly lowered with the increased sererity of HIE and there was significant difference among the groups at the 5th day after birth（ P 〈 0.05）. In the bihrubin levels, between the results measured via serum and skin approaches, there were no significant difference （ P 〉 0.05 ）. Conclusion At the 5th day after birth, the bilirubin level of neonates with moderate and severe HIE were significantly lower than that of neonates with mild HIE, and there was significant difference among the groups. Percutaneous bilirubin detection is an accurate and economical method.
出处
《中国妇幼健康研究》
2006年第2期78-79,共2页
Chinese Journal of Woman and Child Health Research
