摘要
The analyical electron microscopy （AEM） was employed to observe the intratissuelar distribution of polysorbate 80 coated nanoparticles in brain with copper chlorophyll （CC）.and a safe and cheap pigment was used as a marker,AEM analyses show that some nanoparticles are located at the wall of the nicrovasculum in brain,while others are distributed around the nicrovasculum in brain ,These results may support that T-80 coated nanoparticles cross the BBB through mechanisms of endocytosis or transcytosis.
The analyical electron microscopy （AEM） was employed to observe the intratissuelar distribution of polysorbate 80 coated nanoparticles in brain with copper chlorophyll （CC）.and a safe and cheap pigment was used as a marker,AEM analyses show that some nanoparticles are located at the wall of the nicrovasculum in brain,while others are distributed around the nicrovasculum in brain ,These results may support that T-80 coated nanoparticles cross the BBB through mechanisms of endocytosis or transcytosis.
基金
FundedbytheNationalNaturalScienceFoundationofChina(No.30170392and50271029)
