摘要
目的:了解涎腺腺癌发病情况、构成特点,并探讨13例涎腺腺癌的治疗方式和治疗效果,指导临床实践。方法:按照WHO涎腺肿瘤组织学分类标准,对13例经病理确诊的涎腺腺癌部位分布、发病年龄、性别进行回顾性分析,并对其术后生存情况进行长期跟踪随访。结果:腮腺是最主要发病部位。男性患者(61.5%)稍多于女性(38.5%)。涎腺腺癌患者平均发病年龄49.6岁,13例涎腺腺癌患者中位生存时间为8.5年,3年生存率为83.3%,5年生存率为66.7%。结论:涎腺腺癌发病男性占优势,以腮腺最好发,手术治疗为主,首次手术彻底为治疗关键,治疗计划需个性化,患者死亡主要发生于术后6年之内,过后生存时间显著延长。
Objective: To investigate the clinical features, the operative type and therapeutic-efficacy of adenoeareinoma salivary glands. Methods: Thirteen cases of salivary glands adenocarcinoma were reviewed and pathologic diagnosis was based on the WHO Classification. The clinical features were retrospectively analyzed and followed-up for prognosis. Results: Parotid gland was the most common location of salivary adenocarcinoma. In the 13 cases, the average age of onset was 49.6, with a male preponderance. The median survival time, 3-year and 5-year survival rate was 8.5years, 83.3%, and 66.7%, respectively. Conclusions: The male patients predominate in the incidence of adenocarcinoma salivary glands, with parotid as the predilection site, surgical operation as the main treatment, complete initial-operation as the key of the treatment. Individualization is needed in the regimens. The mortality occurs mainly within 6 years after operation, after which the survival time significantly prolongs.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2006年第9期518-520,共3页
Chinese Journal of Clinical Oncology
关键词
涎腺
腺癌
预后
Salivary glands Adenocarcinoma Prognosis