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补肾生血颗粒对肾性贫血大鼠抗氧化作用及血EPO含量的影响 被引量:5

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摘要 目的:探讨补肾生血颗粒对慢性肾衰肾性贫血大鼠的抗氧化作用,改善肾性贫血效果及血EPO含量的影响。方法:采用腺嘌呤建立大鼠贫血模型,随机分为模型对照组、中药治疗组(补肾生血颗粒)、西药治疗组(促红素EPO)、中西药联合治疗组(补肾生血颗粒、EPO联用)。测血RBC、HCT、肾功、超氧化物歧化酶(SOD)及血EPO含量。结果:补肾生血颗粒治疗肾性贫血的效果与EPO无明显差异(P>0.05),稍逊于中西药联合应用组(P<0.05),并能明显降低血BUN、Cr的含量,减轻肾组织病理损害,提高血SOD及EPO的水平(P<0.05)。结论:补肾生血颗粒能有效治疗肾性贫血并能明显改善肾功能,提高血EPO含量,还有增强机体抗氧化能力的作用。
出处 《中医药学刊》 CAS 2006年第5期903-905,共3页 Study Journal of Traditional Chinese Medicine
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