摘要
目的:建立复方益肾颗粒质量标准。方法:采用薄层色谱法对处方中自芍、党参、黄芪进行定性鉴别, HPLC法测定白芍中芍药苷的含量。结果:可鉴别白芍、党参、黄芪,芍药苷在0．105～1．050μg范围内线性关系良好,平均回收率在98．02％～99．51％,RSD在1．1％～1．6％。结论:该方法简便、准确、重现性好,可作为该制剂质量控制方法。
Objective：To establish the quality standard for the granules of nourishing kidney compound （ Fufangyishen）. Methods： Radix Paeoniae Alba, Radix Codonopsis, Radix Astragali were qualified by TLC. The Paeoniflorin concentration in Fufangyishen granules was quantified by HPLC.Results： The major components associated with each herbal material could be separated satisfactorily. Paeoniflorin concentration showed a good linear curve in the range of 0. 105 - 1. 050 μg （ r = 0. 999 9）. The average recovery of paeoniflorin was within 98.02% ～ 99.51% with RSD of 1. 1% ～ 1.6%. Conclusion： These reliable analytic methods are used better in the quality control of Fufangyishen granules.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2006年第8期626-629,共4页
Chinese Journal of New Drugs
关键词
复方益肾颗粒
质量标准
薄层色谱法
高效液相色谱法
Fufangyishen granules
quality standard
thin layer chromatography
high perform- ance liquid chromatography
