摘要
AIM： Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS： Thirty lesions each of hyperdense, isodense and hypodense attenuation compared to normal liver parenchyma were injected into 15 ex-vivo pig livers. All lesions were composed of the same amounts of gelatine containing 0.5 MBq of ^18F-FDG. Following lesion insertion, an interventional needle was placed in each lesion under CT-guidance solely. After that, a PET/CT study was performed. The localization of the needle within the lesion was assessed for CT alone and PET/CT and the root mean square （RMS） was calculated. Results were compared with macroscopic measurements after lesion dissection serving as the standard of reference. RESULTS： In hypo- and isodense lesions PET/CT proved more accurate in defining the position of the interventional device when compared with CT alone. The mean RMS for CT and PET/CT differed significantly in isodense and hypodense lesions. No significant difference was found for hyperdense lesions. CONCLUSION： Combined FDG-PET/CT imaging provides more accurate information than CT alone concerning the needle position in FDG-PET positive liver lesions. Therefore combined PET/CT might be potentially beneficial not only for localization of an interventional device, but may also be beneficial for guidance in interventional liver procedures.
瞄准：在肝损害 interventional 设备放真希望是一项挑战性的任务 CT 是可得到的。我们在 interventional 肝研究为 interventional 设备的本地化调查了联合 PET/CT 图象的潜在的利益。方法：三十损害各个亢奋稠密， isodense 和低亚硫酸钠与正常肝实质相比的稠密的变细被注入 15 个 ex-vivo 猪肝。所有损害由包含 0.5 MBq 的胶的一样的数量组成(18 ) F-FDG。后面的损害插入，一根 interventional 针完全在 CT 指导下面被放在每损害。在那以后， PET/CT 研究被执行。在损害以内的针的本地化独自为 CT 被估计， PET/CT 和根平均数平方(RMS ) 是计算的。结果与在用作参考的标准的损害解剖以后的宏观的大小相比。结果：在低亚硫酸钠 -- 并且 isodense 损害 PET/CT 在定义 interventional 设备的位置证明更精确什么时候与 CT 相比独自一个。为 CT 和 PET/CT 的吝啬的 RMS 在 isodense 和低亚硫酸钠显著地不同稠密的损害。没有有效差量被作出对有利的裁决亢奋的稠密的损害。结论：联合 FDG-PET/CT 成像在 FDG 宠物积极的肝损害有关针位置独自比 CT 提供更精确的信息。因此联合的 PET/CT 可能为一台 interventional 设备的本地化是潜在地有益的不仅，但是可能也为在 interventional 肝的指导有益过程。
