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山西省高碘地区分布特征与高碘危害的流行病学调查 被引量:28

An epidemiological study on the distributive characters and the harm of high water iodine in Shanxi Province
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摘要 目的查清山西省高碘地区分布特征,为病区划分、干预措施实施提供依据。方法在山西省进行20个县(市、区)的水碘及病情调查,甲状腺检查采取触诊和B超法,尿碘测定采用砷铈催化分光光度法,盐碘测定采用砷铈氧化还原法,智力测定采用瑞文测验。结果在调查20个市(县、区)的160个乡镇中,共检测水碘1 872份,有29个乡镇水碘中位数高于150μg/L。高碘乡镇儿童尿碘中位数460.50μg/L,儿童甲状腺(B 超法)肿大率13.08%,平均智商114,合格碘盐食用率72.20%;非高碘乡镇儿童尿碘中位数310.30μg/L,儿童甲状腺(B超法)肿大率7.32%,合格碘盐食用率83.13%,平均智商112。结论山西省在10个市(县、区)的29 个乡镇有高碘分布,高碘乡镇儿童甲状腺肿大率、尿碘中位数、智商都显著高于非高碘乡镇,盐碘仍是导致高碘甲状腺肿的一个重要原因,以停供碘盐为主的防治措施有待进一步落实。 Objective To explore the distribution of high water iodine in Shanxi Province,which will provide basis for determination and classification of the diseased areas and implement of the interfering measurement. Methods Thyroid volume was detected by palpation and B uhrasound,Raven's Test was used to test the intelligent quotient, and eolorimetie eerie-arsenic assay was used for testing urinary iodine and oxidationreduction eerie-arsenic assay for salt iodine. Results 1 872 samples of drinking water were tested in 160 towns in 20 counties, and the.median of water iodine was higher than 150 μg/L in 29 towns. In the areas of high water iodine,the median of urinary iodine was 460.50 μg/L,the goiter rate was 13.08%, the edible rate of qualified iodized salt was 72.20%, and the median of IQ was 114. But in the areas of low water iodine,the indicators above mentioned were 310.30 μg/L, 7.32%, 83.13% and 112 respectively. Conclusions The areas of high water iodine distribute in 29 towns of 10 counties in Shanxi. The levels of goiter, urinary iodine and intelligence quotient in the areas of high water iodine are significantly higher than that of in the areas of low water iodine, respectively. Iodized salt is still the main factor causing high iodine goiter, and the countermeasures, such as stopping salt iodization in the areas of high water iodine should be implemented.
出处 《中国地方病学杂志》 CAS CSCD 北大核心 2006年第3期294-296,共3页 Chinese Jouranl of Endemiology
基金 国家自然科学基金资助项目(30230330)
关键词 过量 分布 流行病学调查 Iodine Excess Distribution Epidemiological investigation
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