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硫酸软骨素在眼优势柱可塑性终止中的作用研究

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摘要 目的:探讨利用电生理学技术研究硫酸软骨素在眼优势柱可塑性终止过程中的作用。方法:取100天龄LongEvans大鼠25只,随机分为正常组、单眼剥夺组、硫酸软骨素酶微注射单眼剥夺组、人工脑脊液微注射单眼剥夺组,然后利用电生理学技术检测4组大鼠初级视皮层眼优势柱的分布。结果:电生理学技术证实正常组、单眼剥夺组及人工脑脊液微注射单眼剥夺组3组大鼠视皮层眼优势柱的分布均为对侧眼优势,而硫酸软骨素酶微注射单眼剥夺组大鼠视皮层眼优势柱的分布为同侧眼优势。结论:硫酸软骨素参与了成年LongEvans大鼠眼优势柱可塑性的终止。
出处 《现代医药卫生》 2006年第12期1786-1787,共2页 Journal of Modern Medicine & Health
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