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肿瘤坏死因子α基因多态性与精神分裂症 被引量：4

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摘要 近来研究表明异常的免疫功能在精神分裂症的发病中起了重要的作用。提示肿瘤坏死因子α(TNFα)基因可能是精神分裂症的易感基因,本文就TNFα基因多态性与精神分裂症的相关性进行综述。
作者 杨琴 司天梅 舒良
机构地区 北京大学精神卫生研究所
出处 《国际精神病学杂志》 2006年第2期77-80,共4页 Journal Of International Psychiatry
关键词 肿瘤坏死因子A 精神分裂症 基因多态性
分类号 R749.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献15

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  • 2Loddick SA, Rothwel NJ. Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin-like growth factor- 1. Proceeding of the National Academy of Sciences of the United States of America. 1999; 96: 9449-9451.
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  • 5Louis E, Franchimont D, Piron A, et al. Tumor necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipolysaccharide (UXS) -stimulated whole blood cell culture in healthy humans. Clin Exp lmmunol. 1998; 113: 401-406.
  • 6Boin F, Zanardini R, pioli R, et al. Association btween-G308A tumor necrosis factor alpha gene polymorphism and schizophrenia. Mol Psychiatry, 2001; 6: 79-82.
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  • 9Schwab SG, Mondabon S, Knapp M, et al. Association of tumor necrosis factor alpha gene. G308A polymorphism with schizophrenia. Schizophr Res. 2003, 65: 19-25.
  • 10杨建中,司天梅,凌炎苏,阮燕,韩永华,王希林,周沫,张鸿燕,孔庆梅,李雪倪,刘萃,张大荣,舒良,张岱.肿瘤坏死因子α基因(TNFα)-G308A多态性与精神分裂症的关联[J].中国心理卫生杂志,2003,17(6):415-417. 被引量：12

二级参考文献21

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共引文献11

同被引文献40

  • 1Kowalski J, Blada P, Kucia K, et al. Neuroleptics normalize increased release of interleukin-1 beta and tumor necrosis factor-alpha from monocytes in schizophrenia[ J ]. Schizophr Res, 2001, 50 ( 3 ) : 169-175.
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  • 4Boin F, Zanardini R, Pioli R, et al. Association between-G308A tumor necrosis factor alpha gene polymorphism and schizophrenia [ J ]. Mol Psychiatry, 2001, 6(1): 79-82.
  • 5Czerski PM, Rybakowski F, Kapelski P, et al. Association of tumor necrosis factor-308G/A promoter polymorphism with schizophrenia and bipolar affeetive disorder in a Polish population [ J ]. Neuropsy- chobiology ,2008,57 ( 1-2 ) : 88-94.
  • 6Duan S, Xu Y, Chen W, et al. No association between the promoter variants of tumor necrosis factor alpha (TNF-alpha) and schizophrenia in Chinese Han population [ J ]. Neurosci Lett, 2004, 366 (2) : 139- 143.
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  • 8Hashimoto R, Yoshida M, Ozaki N, et al. Association analysis of the -308G > A promoter polymorphism of the tumor necrosis factor alpha (TNF-alpha) gene in Japanese patients with schizophrenia [ J ]. J Neural Transm, 2004, 111(2): 217-221.
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  • 10Pae CU, Chae JH, Bahk WM, et al. Tumor necrosis factor-alpha gene polymorphism at position -308 and schizophrenia in the Korean population [ J ]. Psychiatry Clin Neurosci,2003, 57 (4) : 399-403.

引证文献4

二级引证文献10

国际精神病学杂志
2006年 第2期

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