摘要
目的:探讨中药尿毒清在治疗危重症合并肾功能不全患者中的疗效。方法:46例收住急诊重症监护室(E ICU)合并肾功能不全的危重症患者,在给予西医基础治疗基础上加用中药尿毒清,每日30 g口服或鼻饲,连续观察至给药后9 d。记录治疗后3、5、7和9 d血清尿素氮(BUN)、肌酐(C r)、pH值、阴离子间隙(AG)、红细胞计数(RBC)、血红蛋白(Hb)、急性生理学与慢性健康状况评分Ⅱ(APACHAⅡ)等相关指标,比较治疗前后患者上述指标的变化。结果:与治疗前比较,治疗后9 d患者肾功能明显改善,BUN、C r显著降低,RBC升高,AG明显下降(P均<0.05),pH值趋于正常,APACHAⅡ评分下降显著(P<0.05)。结论:尿毒清可改善危重症患者的肾功能,同时可纠正电解质紊乱及酸碱失衡,在危重症患者综合治疗中有一定的意义。
Objective： To investigate the curative efficiency of traditional Chinese medicine Niaoduqing （尿毒清） in treatment of critically ill patients with renal failure （RF）. Methods： Forty-six serious patients with RF in emergency intensive care unit （EICU） were treated with western medicine. Additionally, Niaoduqing was used orally or via nasal tube 30 g/d for 9 days. The parameters including blood urea nitrogen （BUN）, creatinine （Cr）, pH, anion gap （AG）, red blood cell （RBC）, hemoglobin （Hb） and acute physiology and chronic health evaluation Ⅱ （APACHE Ⅱ ） were recorded 3, 5, 7 and 9 days after treatment. Then the changes of the indexes before and after the treatment were analyzed. Results： There were obvious differences in renal function 9 days after treatment compared with that before treatment. BUN and Cr significantly decreased, and RBC increased. AG and APACHE Ⅱ decreased significantly （all P〈0. 05）, and pH had a tendency to be normal. Conclusion： The treatment of Niaoduqing on the critically ill patients combined with RF has obvious improvement for renal function and retards the progression of RF. At the same time, the disorder of electrolyte and the balance between acid and base are retrieved obviously. Niaoduqing may be a very effective traditional Chinese medicine on critically ill patients with RF, and has significance in critical medicine.
出处
《中国中西医结合急救杂志》
CAS
2006年第3期179-181,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
关键词
尿毒清
肾功能衰竭
危重病
Niaoduqing
renal failure
critical illness
