摘要
报告1例以泛发性色素沉着为主要临床表现的蕈样肉芽肿。患者男,41岁。颈部、躯干、四肢色素沉着12年,进行性加重,无自觉症状。皮肤科检查:颈部、躯干、四肢见浅褐色及深褐色斑片,部分皮损呈条索状,轻度苔藓样变。皮损组织病理学检查:真皮内有以淋巴细胞为主的浸润,部分淋巴细胞异形,少量浸润细胞侵入表皮,形成Pautrier微脓肿。免疫组化染色:LCA及CD45RO均(+++)。诊断:蕈样肉芽肿。给予阿维A治疗,皮损略缓解。随访期间病情稳定。
A case of mycosis fungoides （MF）with the hyperpigmentation is reported.The patient was a 41-year-ole man and referred sith skin lesions over the neck,trunk and limbs without any symptom for 12 years.Physical examination revealed light-brown and dark-brown plaques on neck,trunk and limbs.Some of them manifested a slightly lichenoed pattern.The histopathological examination revealed infiltration of lymphocytes in dermis ,which were atypical lymphocytes,A few infiltrate cells entered into epidermis and formed Pautrier＇s microabscesses.The immunohistochemistry showed the positive reactions to LCA（＋＋＋）and CD45RO（＋＋＋）.The patient was diagnosed as MF.He was treated by acitretin capsules and the lesions were relieved slightly.There was no progression of the lesions during the period of following-up.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2006年第6期387-388,共2页
Journal of Clinical Dermatology
关键词
蕈样肉芽肿
色素沉着
mycosis fungoides
hyperpigmentation
