摘要
目的:总结原发性睾丸非精原细胞性生殖细胞肿瘤(NSGCT)的诊断与治疗体会。方法:回顾性分析收治的68例NSGCT临床资料。胚胎癌35例,畸胎瘤11例,卵黄囊瘤3例,绒毛膜上皮癌6例,混合性生殖细胞瘤13例。睾丸无痛性肿大为其主要临床表现。在根治性睾丸切除基础上采用腹膜后淋巴结清扫术(RPLND)及化疗等综合治疗措施。结果:全组患者中随访63例,失访5例。睾丸肿瘤的B超诊断优于CT,腹膜后淋巴结的CT诊断优于B超。3、5年生存率与国内外报道相似。结论:NSGCT在根治性睾丸切除基础上采用RPLND及化疗等综合治疗措施,疗效满意。B超和CT为其诊断和临床分期的主要手段。肿瘤标记物对治疗以及预后判断有一定参考价值。
Objectiw matous germ cell tumors ,e： To evaluate the diagnosis and treatment of primary testicular nonseminomatous germ cell tumors
（NSGCT）. Methods： Sixty-eight cases of NSGCTs were analyzed. There were 35 embryonal carcinomas, 11 teratomas, 3 yolk sac tumors, 6 choriocarcinomas and 13 mixed germ cell tumors. The cardinal clinical manifestation was painless solid enlargement of the testis. Combined therapy, including radical orchiectomy （RO）, retroperitoneal lymph node dissection （RPLND） and chemotherapy, was given. Results： Sixty-three patients have been followed up at 3 and 5 years. B-ultrasound is better than CT in the diagnosis of NSGCT; on the other hand, CT is better than B-ultrasound in the detection of metastasis to retroperitoneal lymph nodes. Survival rates are similar to reports at home and abroad. Conclusion： Combined therapy, including RO, RPLND and chemotherapy is satisfactory. Clinical staging is based on CT or B-ultrasound. Tumor markers are helpful for diagnosis, prognosis and monitoring the therapeutic effect of treatment on NSGCT.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2006年第11期651-653,共3页
Chinese Journal of Clinical Oncology
