摘要
目的验证龙芩草喷雾剂抗流感病毒A1型(H1N1)的作用。方法将实验小鼠感染流感病毒,给药组予龙芩草喷雾剂,阳性对照药组给利巴韦林,病毒对照组给生理盐水,计算死亡率、保护率、延长生命率及肺部病变抑制率,并将所得数据进行统计学处理。结果龙芩草喷雾剂能显著降低感染流感病毒A1型(H1N1)小鼠肺部病变抑制率、死亡率,并提高延长生命率,统计学处理结果显示,给药组和阳性对照药组与病毒对照组相比具有显著性差异(P<0.01)。结论龙芩草喷雾剂具有显著的抗流感作用。
Objective To test the antagonism of Longqincao Spray on influenza virus A1 （H1N1）. Method The experimental mice were infected with influenza virus, and then the treatment group was given Longqincal Spray, the positive remedy control group was given ribavirin and the virus control group was given physiological saline. The mortality, protection rate, life-prolonged rate and pneumopathy inhibitory rate were calculated and then the data were treated by statistics Result Longqincao Spray deoroased significantly the pneumopathy inhibitory rate and mortality, increased the life-prolonged rate in mice infected with influenza virus A1（H1N1）. The result of statistics showed that the difference between the treatment group and control group was significant （P〈0.01）. Conclusion Longqincao Spray has an obvious antagonism on influenza virus through inhibiting their replications.
出处
《北京中医药大学学报（中医临床版）》
2006年第3期4-6,共3页
Journal of Beijing University of Traditional Chinese Medicine
基金
"十五"国家科技计划研究课题项目(No.2004BA721A46)
关键词
龙芩草喷雾剂
流感病毒
清热解毒
活血化瘀
祛痰止咳
小鼠
Longqincao Spray
influenza virus
clearing away heat to remove toxin
activating blood to resolve stasis
expelling phlegm to stop cough
mice
