摘要
近年来对维生素D受体(VDR)基因和骨量关系的研究颇有争议。有许多研究认为维生素D受体基因多态性与骨量有关联。但还有一部分研究未能证实VDR基因多态性与骨量的关联。本文就VDR基因与钙吸收、骨量、药物治疗的关系和VDR基因的协同作用以及与其它基因、环境因素的交互作用对骨量影响的研究进展进行了综述。
The association between vitamin D receptor gone polypmorphisms and bone mass is controversial. Many studies have found polymorphism of vitamin D receptor (VDR) gone be associated with bone mass. But some studies show no association between vitamin D receptor gene polymorphism and bone mass, The relationships among vitamin D receptor gene and calcium absorption, bone mass, drug treatment are reviewed in this article, The interaction between genetic, environmental factors to bone mass is also reviewed.
出处
《卫生研究》
CAS
CSCD
北大核心
2006年第3期370-373,共4页
Journal of Hygiene Research
基金
国家自然科学基金项目(No.30471453)