摘要
目的观察改良颈7移位术修复二组受损神经的电生理变化。方法建立大鼠颈7改良移位术模型(同侧颈7神经根后股,经同侧尺神经作为桥接神经分为两股与肌皮神经和正中神经内侧头缝合),并与传统单组移位组进行神经电生理测定和比较。结果移位神经的各项电生理指标显示:术后早期(2～6周),颈7二组神经移位组神经再生劣于同时间段单组移位组。随观察时间的延长,术后8周起, 二组神经移位组肌电动作电位潜伏期及最大诱发电位波幅指标逐渐接近单组移位组和正常对照组,至12 周上述指标与各组差异无统计学意义(P>0．05)。结论大鼠改良颈7移位术电生理变化和传统单组移位术相近,说明颈7具有良好的再生潜力,可同时支配两组受损神经。
Objective To test the feasibihty of rescuing 2 impaired nerves by C7 nerve transfer （modified C7 nerve neurotization）. Methods Using adult male Sprague-Dawley rats, a C7 nerve double-neurotization model was established. Ipsilateral C7 nerve root was transferred to both musculocutaneous nerve and medial head of the median nerve via an ulnar nerve graft. At postoperative 2, 4, 6, 8, and 12 weeks electrophysiolagical examination was conducted and compared with C7 single transfer. Results Maximum amplitude and nerve-muscle latency of evoked motor action potential of reinnervated biceps and flexor digitorum profundus muscles showed that nerve regeneration in double neurntization group was not as good as that of single neurntization in the early postoperative period （2-6 weeks）. As the postoperative interval prolonged, most of the parameters in double-ncurotization group approximated to those in the single neurotization group and normal control group, thus indicating C7 nerve contains enough nerve fibers to provide sufficient regeneration for 2 recipient nerves. Conclusion Compared to single neurotization, C7 nerve doubleneurotization has the advantage of restoring 2 nerve function at the same time. This implicates its future clinical application in treating severe brachial plexus avulsion injuries.
出处
《中华手外科杂志》
CSCD
北大核心
2006年第3期177-179,共3页
Chinese Journal of Hand Surgery
关键词
臂丛
脊神经根
神经移位
电生理学
大鼠
Brachial plexus
Spinal nerve roots
Nerve transfer
Electromyography
Rats
