摘要
目的:对比观察采用丹参注射液预防人工全髋关节置换(THR)术后下肢深静脉血栓形成(DVT)的临床效果。方法:将1998年1月至2004年8月行人工全髋关节置换术的患者随机分为未用药组和用药组,其中未用药组56例,未预防性使用任何药物;用药组60例,围手术期给予丹参注射液预防性治疗。术后第7、14天,两组患者均行患肢彩色多谱勒超声检查,了解DVT形成情况及两组术后DVT的发生率。结果:未用药组中有23例DVT阳性,DVT的发生率41.1%,用药组中有11例DVT阳性,DVT的发生率18.3%,两组比较,差异有统计学意义(P<0.05)。未用药组近端DVT的发生率为14.3%,用药组近端DVT的发生率为1.7%,两组比较,差异有统计学意义(P<0.05)。用药组未发现术中术后出血增多以及药物不良反应。结论:丹参可显著降低人工全髋关节置换术后下肢深静脉血栓的发生,且具有良好的安全性。
Objective：To evaluate the efficacy and safety of Salvia miltiorrhiza Bge in preventing deep--vein thrombosis （DVT） after total hip replacement. Methods：From January 1998 to August 2004, we performed total hip replacement for 56 control patients and for 60 patients who had been given Salvia miltiorrhiza Bge injection for prevening deep--vein thrombosis. All the patients received Color Doppler ultrasonography examination 7 and 14 days after operation. Results： DVT occurred in 18. 3 % of the Salvia miltiorrhiza Bge patients and the reduction was significant（P〈0.05 ） compared to the control group. The incidence of proximal DVT was also reduced significantly（P〈0.05） from 14.3% of the control group to 1.7% of the Saliva miltiorrhiza Bge group. Conclusions：Salvia miltiorrhiza Bge can significantly reduce the incidence of deep--vein thrombosis after total hip replacement.
出处
《中国中医骨伤科杂志》
CAS
2006年第3期14-17,共4页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
关节成形术
置换
髋
深静脉血栓
丹参
术后
Arthroplasty Replacement Hip Deep vein thrombosis Salvia miltiorrhiza Bge
