摘要
目的:临床研究硫糖铝佐治急性放射性肠炎的疗效和不良反应。方法:治疗组38例用硫糖铝1.0g及思密达3.0g,每日3次;对照组51例用思密达3.0g,每日3次,1周为1疗程。采用卡方检验进行疗效比较。结果:治疗组有效率为92.1%;对照组有效率为84.3%。两组间疗效比较差异有显著性(χ2=6.2,P<0.05)。结论:硫糖铝可加速受损肠粘膜的修复功能,并具有良好的止痛、止血效果,无明显毒副作用,使用方便,故应用其佐治急性放射性肠炎具有进一步研究和应用价值。
Objective： To research the clinical effects and side - effects of sucmlfate on acute radiation induced enterocolites. Methods： Smecta 3.0 and sucralfate 1.0g were each time in subject group composing of 38 patients who were observed during radiotherapy of malignancies, while there were 51 patients taking only smecta 3.0g each time in the control group, both group took drugs three times every day, one week is a therapeutic course. Statistical analysis was completed by Chi - squared test.Result： The effective rate was 92.1% in subject group, and was 84.3% in control group.There were significant difference between two groups （X^2 = 6.2, P 〈 0.05） .Conclusion： Sucralfate can enhance plerosis function of intestinal impairing mucosa and have good effect of relieving pain and stopping hemorrhage, it is an effective, convenient and slight side - effects drug for controlling radiation - induced enterocolitis. So it is worthy of further study and clinical application extensively.
出处
《宜春学院学报》
2006年第2期92-93,共2页
Journal of Yichun University
