摘要
将无支气管和肺疾病的食管癌患者１７例分为吸烟组和非吸烟组，术前进行肺功能检查，术后对肺组织进行病理检查。吸烟组病理总分、炎性细胞浸润、结缔组织增生均明显高于不吸烟组。吸烟组小气道平均直径为０．５９１８±０．１３２７ｍｍ明显小于非吸烟组的０．７８２３±０．２１３５ｍｍ。小气道病理改变与肺功能检查相关顺序依次为Ｖ５０、Ｖ２５、ＭＭＥＦ和ＦＥＶ１％。
Seventeen cases suffered from esophagal cancer without bronchitis and lung diseases were studied. These patients' pulmonary function were examined before operation and small airways were observed after operation by optical microscope. Seventeen cases were divided into two groups by smoking and nonsmoking. The results were demonstrated as follows: total pathologic score in smoking group was significantly higher more that of nonsmokerin (P<0. 05),the inflammation cell infiltration in smoking group was significantly higher than that of nonsmoking group(P<0. 05), the fibrosis in smoking group was significantly more than that of nonsmoking (P<0. 025). The mean diameter of small airways in smoking group was significantly smaller than that of nonsmoking group(P<0. 05). Total pathologic score had the most significant correlation with V50 (r=-0. 5039, P<0. 05), it was also SIGnificantly to correlate with V25 (r=- 0.4850, P<0.01), MMEF (r=-0. 4353, P< 0.025), FEV1% (r=-0. 3396, P<0. 05).
出处
《山东医科大学学报》
1996年第1期59-62,共4页
Acta Academiae Medicinae Shandong
关键词
小气道
肺功能
病理学
吸烟
Lung
Small airways
Lung function
Pathology, clinical
Smoking
