摘要
以硫代乙酰胺(TAA)与Cd2+在碱性溶液中反应制备了CdS荧光纳米粒子,该纳米粒子的荧光强度强烈的被药物成分柳氮磺吡啶所淬灭,建立了一种高选择性的测定柳氮磺吡啶的荧光分析新方法.结果表明,在pH值为11.2时,对于柳氮磺吡啶的检测下限可达到1×10-7g/mL,线性范围为5.0×10-7g/mL^1.0×10-4g/mL.方法已用于药片中柳氮磺吡啶的测定.
CAS nanoparticle was synthesized by reaction of Cd^2 ＋ and TAA （thiacetamide） in alkaline medium. Based on the fluorescence intensity of CdS nanoparticle weakened by sulfasalazine, a highly selective fluorescence method for sulfasalazine has been developed. The result showed that the detection limit was 1 × 10^-7 g/mL and the linear ranged from 5.0 × 10^-7 ～ 1.0 × 10^-4 g/mL when the pH was in 11.2. This method has been successfully applied to analyzing of sulfasalazine in tables.
出处
《陕西师范大学学报（自然科学版）》
CAS
CSCD
北大核心
2006年第2期74-76,79,共4页
Journal of Shaanxi Normal University：Natural Science Edition
基金
国家自然科学基金资助项目(20575040)
