摘要
目的探讨^(99m)Tc腮腺动态显像诊断干燥综合征的价值。方法对临床诊断为干燥综合征(SS)的40例患者以及29例对照组进行^(99m)Tc腮腺动态显像,以摄取值和分泌率为定量指标,利用受试者工作曲线(ROC)确定摄取值和分泌率的最佳临界点,根据ROC曲线下面积(AUC^(ROC))评价^(99m)Tc腮腺动态显像对SS的诊断价值。结果摄取值的最佳诊断值为5．5～5．7,分泌率的最佳诊断值为0．20。在最佳诊断值水平摄取值和分泌率对诊断干燥综合征有较高的敏感度(86．2%～89．7%)。摄取值的特异度较低(63．4%～65．9%),分泌率的特异度较高(82．9%～85．4%)。摄取值和分泌率AUC^(ROC)的分别为0．780/0．776及0．905/0．899,较接近1．0。结论^(99m)‰Tc腮腺动态显像对诊断干燥综合征具有较好的价值。
Objective The purpose of this study is to determine whether the quantitative parameters of salivary gland scintigraphy are useful in the diagnosis of Sjoegren＇s syndrome （SS）. Method Forty patients with SS and 29 control subjects underwent salivary gland scintigraphy. Two indices, uptake ratio and maximum secretion were mearsured. The optimal cut-points of both indices were derived from receiver operative characteristic curve （ROC）. The diagnostic value of the indices was assessed by the area under ROC curve （AUC^ROC）. Results The optimal cut-point of uptake ratio was 5.5-5.7. The optimal cut-point of maximum secretion was 0.20. The sensitivities of both indices were 86.2%-89.7%. The specificity of uptake ratio was 63.4 %-65.9%. The specificity of maximum secretion was 82.9%-85.4%. The AUC^ROC of uptake ratio was 0.780/0.776. The AUC^ROC of maximum secretion was 0.905/0.899. Conclusion The quantitative parameters of salivary gland scintigraphy may be useful in the diagnosis of Sjoegren syndrome.
出处
《中华风湿病学杂志》
CAS
CSCD
2006年第6期335-337,共3页
Chinese Journal of Rheumatology
关键词
干燥综合征
腮腺
放射性核素显像
Sjoegren＇s syndrome
Parotid gland
Radionuclide imaging
