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254株肠球菌的分布及耐药性分析 被引量:7

Distribution and drug resistance analysis of 254 strains of enterococcus
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摘要 目的了解该院2001年1月~2004年12月临床分离的肠球菌的菌种分布和耐药情况。方法采用梅里埃API细菌生化鉴定系统对肠球菌进行鉴定,用K-B法进行药敏测定。结果254株肠球菌中以粪肠球菌和屎肠球菌分离率最高,分别占76.8%和14.6%,其他肠球菌占8.6%;肠球菌对万古霉素的耐药率为零,对青霉素、氨苄西林的耐药率,粪肠球菌为8.7%和7.7%,屎肠球菌均为89.2%;粪肠球菌和屎肠球菌的耐药率对高浓度庆大霉素分别为34.4%和56.8%,对呋喃妥因分别为9.7%和29.7%,对左氧氟沙星分别为26.7%和75.7%,对氯霉素分别为40.0%和29.7%,对红霉素分别为79.0%和91.9%。结论引起医院感染的肠球菌主要是粪肠球菌和屎肠球菌,对青霉素类抗生素的耐药性屎肠球菌明显高于粪肠球菌,未检出耐万古霉素的肠球菌。 [Objective] To investigate the distribution and drug resistance of enterococcus isolated from clinical specimens. [Method] API was used for identifying enterococcus and K-B method was used in drug sensitivity tests. [Results] Totally 254 strains of enterococcus were isolated, the isolation rates of E.faecalis, E.faecium and other kind of enterococcus were 76.8%, 14.6% and 8.6% respectively. Enterococcus were all sensitive to Vancomycin. The rates of drug resistance to Penicillin and Ampicillin were 8.7% and 7.7% respectively on E.faecalis and 89.2% on E. faecium. The rates of drug resistance to Gentamicin with high concentration on E.faecaois and E.faecium were 34.4%, 56.8% respectively; to Nitrofurantoin were 9.7% and 29.7% respectively; to Levofloxacin were 26.7% and 75.7%; to Chloramphenicol chloromycetin were 40.0% and 29.7%; to Erythromycin were 79.0% and 91.9%. [Conclusions] Enterococcus, resulted in hospital infection, mostly were E.faecalis and E.faecium. The rates of drug resistance to antibiotics as Penicillin on E.faecium were higher than on E.faecalis. Enterococcus resisted to Vancomycin were not isolated.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2006年第11期1682-1684,共3页 China Journal of Modern Medicine
关键词 肠球菌 分布 抗生素 耐药性 enterococcus distribution, antibiotics drug resistance
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  • 1李仲兴 郑家齐.诊断细菌学[M].香港:黄河文化出版社,1992.295-297.
  • 2周笋洪 万汝根.肠球菌MIC检测及意义评价[J].上海医学检验杂志,1998,13(3):130-130.
  • 3汪复.-[J].抗感染化疗杂志,1997,3:75-78.
  • 4Susan JK, Don BC, Susan MK, et al. Detection of the High-Level Aminoglycoside Resistance Gene aph(2")-I b in Enterococcus faecium[J]. Antimicrobial Agents and Chemotherapy, 2000, 44 (10): 2876-2879.
  • 5Fontana, R. A. Grossata, L. Rossi, and Y. R. Cheng, et al. Transition from resistance to hypersusceptibility to β-lactam antibiotics associated with loss of a lower-affinity penicillin- binding protein in a Streptococcus faecium mutant highly resistant to penicillin [ J]. Antimicrob Agents Chemother, 28: 678-683.
  • 6M. Fines, B. Perichon, and P. Reynolds, et al. VanE, a New Type of Acquired Glycopeptide Resistance in Enterococcus faecalis BM 4405[J]. Antimicrobial Agents and Chemotherapy, 1999, 43 (9): 2161-2164.
  • 7Chow JW, Donaedian SM, Zervos MJ. Emergence of increased resistance to quinupristin/dalfopristin during therapy for enterococcus faecium bacteremia [J]. Clin Infect Dis, 1997, 24: 90.
  • 8[4]National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing[S]. Twelfth informantional supplement. 2002. 21(1): M100-s12.
  • 9[5]Udo EE, Al Sweih N, John P, et al. Antibiotic resistance of enterococci isolated at a teaching hospital in Kuwait[J]. Diagn Microbiol Infect Dis, 2002, 43(3): 233-238.
  • 10[7]Livermore DM, Winstanley TG, Shannon KP. Interpretative reading: recognizing the unusual and inferring resistance mechanisms from resistance phenotypes[J]. J Antimicrob Chemother, 2001, 48, Suppl 1: 87-102.

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