摘要
目的了解洞庭湖区不同血吸虫病流行环境渔民血吸虫病肝纤维化发生情况. 方法用便携式B超诊断仪对3种不同类型环境血吸虫病流行区的911名渔民进行肝实质及门脉纤维化分级诊断,使用Excel和SPSS 11.0作统计学分析.结果在3种不同类型环境中,洲垸型和洲岛型男性肝纤维化发生率均高于女性（P均〈0.01）,但未定居型肝实质纤维化发生率男、女性差异无显著性（P＞0.05）.肝实质纤维化发生率依次为：未定居型＞洲岛型＞洲垸型,而肝门脉纤维化发生率依次为：洲岛型＞未定居型＞洲垸型.肝实质纤维化发生率洲垸型和洲岛型均以50～60岁年龄组为最高,未定居型以40～50岁年龄组为最高;肝门脉纤维化发生率洲垸型以60～岁年龄组为最高,洲岛型和未定居型均以30～40岁年龄组为最高.结论未定居型及洲岛型渔民肝纤维化程度重于洲垸型,需要加强对未定居型及洲岛型渔民的防治.
Objective To explore the relationship between the degree of hepatic fibrosis in fishermen with schistosomiasis japonica and the different environmental types within the Dongting Lake endemic area. Methods A total of 911 subjects with schistosomiasis from three different environmental types within the Dongting Lake endemic area was investigated to determine the degree of hepatic fibrosis by B-ultrasonography. The data were analyzed with SPSS 11.0 and Excel. Results Among three different environmental types, the rates of men with hepatic fibrosis were significantly higher than those of women except the rate of hepatic parenchymatous fibrosis in the non-land-house type. The rates of hepatic parenchymatous fibrosis were decreased progressively ranging from the non-land-house type, island type to inner embankment type ; however, the rates of serious hepatic periportal fibrosis were decreased progressively ranging from the island type, non-land- house type to inner embankment type. The age with the highest rate of hepatic fibrosis in the non- land-house type was less than those of island type and inner embankment type. The rate of hepatic fibrosis in the 〈30-year-old group in the non-land-house type was higher than those of the island type and inner embankment type. Conclusions The degree of hepatic fibrosis in fishermen is related to the environment types where they lived （non-land-house type〉island type〉inner embankment type）. The prevention and control measures for schistosomiasis of fishermen should be strengthened.
出处
《中国血吸虫病防治杂志》
CAS
CSCD
2006年第3期189-191,196,共4页
Chinese Journal of Schistosomiasis Control
基金
国家高技术研究发展计划(863计划)(2004AA2Z3610)
关键词
日本血吸虫病
渔民
环境类型
肝实质纤维化
门脉纤维化
洞庭湖区
Schistosomiasis japonica
Fishermen
Environmental types
Hepatic parenchymatous fibrosis
Periportal fibrosis
Dongting Lake region
