摘要
选取平均体重18～20g左右，公、母各半的昆明系小白鼠64只，随机分为4组，每组16只，进行35d的亚慢性毒性饲养试验。A组为对照组，饲喂小白鼠基础日粮。B、C、D组为试验组，分别饲喂用10％、20％、40％的构树叶粉取代等量基础日粮的试验日粮。结果表明：D组的血清尿素氮（BUN）含量和C、D组的碱性磷酸酶（ALP）活性显著高于A组（P〈0．05），D组的谷丙转氨酶（ALT）极显著高于A组（P〈0．01）；D组组织切片可见肝、肾组织有轻度的病理变化。B、C组朱见明显毒性变化。
64 Kunming System small white rats, half males and half females, with average weight of about 18-20 g were selected and randomly divided into 4 groups, 16 rats for each group, and a subehronic toxicity feeding test was carried out for 35 days. Group A was a control group fed on basal diets for small white rats. Group B, C and D were trial groups fed on 10% , 20% and 40% trial diets of papermulherry leaf meal respectively instead of equivalent basal diets. The results showed that the content of blood serum urea nitrogen （BUN） in Group D and the activity of alkali phosphatase （ALP） in Group C and D were significantly higher than that in Group A（P 〈0.05）, and glutamatepyruvate transaminase （ALT） in Group D was extremely significantly higher than that in Group A （P 〈 0.01） ; a light pathologic change of liver and kidney organs in Group D could be seen through organ section, while no any significant toxic change in Group B and C.
出处
《粮食与饲料工业》
CAS
北大核心
2006年第6期30-32,共3页
Cereal & Feed Industry
基金
广西自然科学基金(桂科基0575007)
关键词
构树叶
小白鼠
毒性试验
生化指标
papermulberry leaf
small white rat
toxMty test
biochemical index
