摘要
目的探讨MRI对肝硬化伴肝癌和非典型性结节的敏感性.方法74例肝硬化患者肝移植前90d内行MRI检查,并同肝移植术后病理切片作对照.所有患者检查前均不知其有无肝癌,FLASH/T1WI、TSE/T2WI序列、动态3期增强扫描被获得.结果病理发现13例患者共21处肝脏有恶性病变,MRI发现其中12/21个恶性病变,敏感性为57.1%,其中发现87.5%（7/8）≥2cm的病变,44.4%（4/9）1～2cm的病变,25.0%（1/4）＜1 cm的病变;对≥2cm和＜2cm组的恶性病变的差异有统计学意义（P＜0.05）.病理检查发现14例患者（14/74）共47个DN,MRI诊断9/47个DN病变,敏感性仅19.1%.结论MRI对肝硬化伴＞2cm的肝癌敏感性较好,但对＜2cm的肝癌及非典型性结节敏感性较差.
Objective To study the sensitivity of MRI in the diagnosis of hepatocelhdar carcinoma （HCC） and dysplastic nodules （DN） using explantation correlation in patients with cirrhosis. Methods Seventy - four patients with liver cirrhosis were examined using MRI 90 days before liver transplantation. FLASH/T1WI, TSE/T2WI, and dynamic gadolinium- enhanced stage m MRI images were obtained. Results Of 74 patients, 13 had hepatocellular carcinoma with pathological evidence, MRI imaging discovered 12 of 21 malignant lesions; the sensitivity of MRI in detecting hepatocellular carcinoma larger than 2 cm was 57.1%. MRI imaging discovered 7of 8（87.5% ） lesions larger than 2 cm, 4 of 9 （44.9%） lesions sized 1 ～ 2 cm, 1 of 4（25.0% ） lesions smaller than 1 cm; the difference in sensitivity between 〉12 cm and 〈 2 cm groups was statistically significant（ P 〈0.05）. MRI imaging discovered only 9 of 47 DN,with a sensitivity of 19.1% .Conclusions MRI is sensitive in diagnosis of the patients with cirrhosis accompanied by hepatocellular carcinoma larger than 2 cm, but is not sensitive in detecting HCC smaller than 2 cm and DN.
出处
《武警医学》
CAS
2006年第5期341-345,共5页
Medical Journal of the Chinese People's Armed Police Force
关键词
磁共振成像
肝硬化
肝癌
非典型性结节
MRI Liver cirrhosis Hepatocellular carcinoma Dysplastic nodules
