摘要
目的为解决新生儿脐带血TSH水平与其他指标的分离现象,建立新生儿脐带血TSH切点值。方法选择近年来开展新生儿TSH筛查的部分市县,将盐碘合格率>90%,儿童尿碘中位数>100μg/L,并且未投服过碘油的地区认定为碘营养正常地区,采用百分位数法确定新生儿脐带血TSH切点值。结果浙江省正常地区新生儿脐带血TSH切点值(第97%分位值)为9.72mU/L,高于国际标准5mU/L。各地区间结果有差异,新生儿性别对新生儿脐带血TSH无影响。结论建立新生儿脐带血TSH切点值对碘缺乏病监测及新生儿甲低筛查均有重要意义,有必要建立适合本地区的新生儿脐带血TSH切点值。
Objective To explore the reference value threshold of neonatal cord blood TSH. Methods The Zhejiang IDD surveillance results from some counties and cities were selected according to where the recent years iodine fortified salt met standard rate 〉90%, children median urinary iodine level 〉 100μg/L, and did net have administrate iodine oil. The 97% percentile value was used as the determined reference value threshold. Results The referencevalue threshold （cut- off point） of neonatal cord blood TSH for normal iodine nutrition districts in Zhejiang was 9. 72mU/L, which was 5mU/L higher than that of the international standard. The results of different areas within Zhejiang Province had Some variances. Conclusions It is important to explore reference value threshold of neonatal cord blood TSH for IDD surveillance and screening of neonatal hypothyroidism. It is necessary to establish our own cord blood TSH cut - off point.
出处
《实用预防医学》
CAS
2006年第3期605-606,共2页
Practical Preventive Medicine
关键词
促甲状腺激素
正常值范围
脐带血
Thyroid stimulating hormone （TSH）
Reference value range
Cord blood
