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肺心病患者血清甲状腺素含量变化及其临床意义 被引量:2

Serum Levels of Thyroid Hormones in Patients With Cor Pulmonale
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摘要 目的探讨75例无甲状腺疾病的肺心病患者血清三碘甲状腺原氨酸(T3)、血清甲状腺素(T4)和血清促甲状腺激素(TSH)的含量变化及其关系。方法检测75例肺心病患者血清T3、T4和TSH含量,另选80例健康体检者作为正常对照组。结果肺心病患者血清T3降低,与正常对照组比较,P<0.01,血清T4与正常对照组比较P>0.05。有肺性脑病、消化道出血严重并发症时,低T3血症尤为严重,P<0.01。且多伴有低T4血症,P<0.05,血清T4血症越低,病死率越高。结论血清T3、T4含量可作为判断肺心病轻重和预后指标之一。 Objective To investigate blood levels of T3, T4, and TSH in patients with cor pulmonale and their correlations. Methods Blood levels of T3, T4, and TSH in 75 patients with cor pulmonale were detected and compared with 80 healthy adult subjects. Results The levels of T3 in patients with cor pulmonale were significantly lower than those of the control group (P〈 0.01 ), but T4 not. T3 levels were further decreased when the patients complicated with pulmonary, cerebral syndrome, gastrointestinal hemorrhage (P〈0.01); and levels of T4 were decreased also (P〈0.05). Conclusion Blood levels of T3, and T4 might be clinical useful indicators of severity and prognosis of cor pulmonale.
作者 罗志远
出处 《实用预防医学》 CAS 2006年第3期740-741,共2页 Practical Preventive Medicine
关键词 肺心病 血清甲状腺素 含量变化 Cor pulmonale Thyroid Hormone Clinical significance
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参考文献3

  • 1slag MF,Morley JE,Elson MK,et al,Hypothyroxincmia in critically ill in patients as a predictor of tagh mortality[J].JAMA,1991,245:43.
  • 2Gomberg-Maitland M,Frishman WH.Thyroid hormone and cardiovascular disease[J].Am Heart J,1998,135:187 196.
  • 3lervasi G.Pingitore A.Landip.Low T3 syndrom:a strong prognostic predictor of death in patients with heart disease[J].Circulation,2003,107(5):708-713.

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