摘要
目的探讨彩色多普勒超声在预测鼻咽癌颈部转移淋巴结放疗中敏感性的应用价值。方法对138例首程放疗的鼻咽癌患者的颈部转移淋巴结行放疗前、放疗中彩色多普勒超声检查,了解其血供情况,测定有关血流参数,定期检查淋巴结转移灶消退程度和速度。结果鼻咽癌颈部转移淋巴结血供丰富者,放疗疗效优者为89.7%,明显高于血供中等者(70.0%)、血供贫乏者(50.0%)(P<0.05),血供与病灶消退呈正相关关系;病灶直径<4cm者,放疗疗效优者为90.6%,直径≥4cm者为50.0%(P<0.05),病灶消退与本身大小呈负相关(P<0.05)。结论彩色多普勒超声可初步作为鼻咽癌颈部转移淋巴结放疗敏感性预测指标之一。
Objective To investigate the value of perfusion data measured by color doppler flowing imaging in predicting the radiosensitivity of the metastatic cervical lymph node of nasopharyngeal carcinoma. Methods The metastatic cervical lymph nodes in 138 cases of nasopharyngeal carcinoma were studied with color Doppler flowing imaging （CDFI） by measuring the blood supply and bloodstream parameters before and during radiotherapy. The regressive degrees and rates were regularly checked. Results The radiotherapeutic effect in the lymph node with the abundant blood supply（89.7 %） is superior to the lymph node with the middle or poor blood supply（70.0 % or 50.0 %）. The difference is significant（P 〈 0.05）. The regression of cervical lymph nodes was positively correlated with the blood supply. The longer the diameter of cervical lymph nodes was, the well the radiotherapeutic effect（≥4 cm vs 〈4 cm; 50.0 % vs 90.6 %） was. The regression of cervical lymph nodes was negative correlated with the size of them（P 〈 0.05）. Conclusion Measuring with CDFI for the change of metastatic cervical lymph nodes＇ blood supply during the radiotherapy may be one of the targets of initial calculation radiation effect.
出处
《肿瘤研究与临床》
CAS
2006年第6期393-394,共2页
Cancer Research and Clinic
基金
广东省医学科学技术研究基金资助项目(B2002093)
关键词
彩色多普勒超声
鼻咽癌
颈部转移淋巴结
放疗敏感性
Color doppler flowing imaging
Radiosensitivity
Metastatic cervical lymph node
Nasopharyngeal carcinoma
