摘要
目的探讨淋巴结血管平滑肌瘤性错构瘤的组织学及免疫组化特征。方法对10例淋巴结血管平滑肌瘤性错构瘤进行组织病理学及免疫组化观察,并结合文献进行讨论。结果光镜下见淋巴结部分结构保存,部分间质胶原化,内见厚壁血管及小血管增生,外周为不规则增生的平滑肌束,层次多少不等,平滑肌细胞分化良好,未见核分裂象和坏死。免疫表型显示平滑肌细胞SMA、desmin阳性,HMB45、ER、PR均阴性。结论淋巴结血管平滑肌瘤性错构瘤较为罕见,临床主要表现为腹股沟淋巴结肿大,依据组织病理学及免疫组化染色可作出明确诊断。
Purpose To study the histological and immunohistochemical characteristics of angioleiomyomatous harmatoma in the lymph nodes. Methods Ten cases of angioleiomyomatous harmatoma in the lymph nodes were investigated by using hematoxylin-eosin stain and immunohistochemistry（SP methods）. The related literatures were reviewed and discussed. Results The harmatoma consisted of partly residual architecture of lymph node with stromal collagenization, proliferative blood vessels with thickened wall and surrounded by irragular hyperplasia of smooth muscle bandies. The smooth muscles were well-differentiated without mitosis and necrosis. Immunohistochemical staining showed that smooth muscle cells were positive for SMA and desmin, but negative for HMB45, ER and PR in all the cases. Conchlsions Angioleiomyomatous harmatoma is very rarely in lymph nodes, which shows enlarged lymph nodes in the inguinal region without other specific clinical characteristics. The diagnosis can be made according to the histological characteristics and immunohistochemical findings.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
2006年第3期291-293,共3页
Chinese Journal of Clinical and Experimental Pathology
