摘要
目的总结Ⅰ和Ⅱ期乳腺癌的病理类型与外科治疗方案。方法 对1990年6月-2003年6月收治的137例Ⅰ和Ⅱ期乳腺癌的临床资料进行回顾性分析并进行随访。结果 实施Halsted手术40便,腋下淋巴结转移率为37.5%(15/40);实施保留胸大小肌的改良根治术79便,腋下淋巴结转移率为27.9%(22/79);保乳手术18例,腋下淋巴结转移率为11.1%(2/18)。死于肿瘤复发术与远处转移17便,其中改良根治术10例(13.2%,10/7),Halsted手术4例(12.1%,4/33),保乳手术3例(16.7%,3/18).Halsted手术和改良根治术的局部复发率与死于肿瘤复发与远处转移率,差异无统计学意义(P〉0.05)。结论 改良根治术与Halsted手术的肿瘤复杂与远处转移无明显差异,但保乳手术对于女性的躯体完整性损伤小,有待探索,应改进Ⅰ和Ⅱ期乳癌外科治疗方案,加强术后辅助治疗,追求微创化、个体化,结合东方女性的乳房特点,积极推进保乳手术的进程。
Objective To discuss the pathology and the surgical therapy of stage Ⅰ and Ⅱ breast careino ma. Methods Therapeutic data of 137 patients with breast earcinoma on stage Ⅰ and Ⅱ were summarized and analysised retrospectively, and the patients were followed up between June 1990 and June 2003. Results We have made the surgical operation of Halsted 40 cases,the transfer rate of axillary lymph node was 37.5% (15/40) ,79 patients who received modified radical mastectomy the transfer rate of axillary lymph node was 27.9% (22/79)%. Eighteen patients who received breast conser vation surgery the transfer rate of axillary lymph node was 11. 1% (2/18). Dying of the tumor relapses and transfer with distant place were 17 eases, amnng them the modified radical masteetonly were 10 cases .( 13.2%, 10/76) ;and surgical operation of Halsted were 4 cases( 12. 1% ,4/33 ) ;and breast conservation surgery were eases ( 16, 7% ,3/18 ). The two methods of modified radical mastectomy and the surgical operation of Halsted have no great difference in the relapses rate and the mortality in the tnmor relapses and transfer with distant place. Conclusion The surgical operation of Halsted,modified radical masteetomy have no great differellce in the relapses rate and the rate of transfer with distant place. But the breast conservation surgery was small hurt to female's body,we should investigate it and improve the stage Ⅰ and Ⅱ breast eareinoma's surgery cure project,and enhance the treatment after surgery, pursue the tiny hurt and " individuation", combined with the eastern female's breast characteristics, push forward the progress of the breast conservation surgery.
出处
《中原医刊》
2006年第13期6-8,共3页
Central Plains Medical Journal
关键词
乳腺癌
外科治疗
病理
保乳手术
Breast carcinoma
Surgical therapy
The pathology
Breast conservation surgery