摘要
目的:探讨老年糖尿病患者合并非糖尿病性肾病的临床与病理特点。方法:回顾性分析了2000年7月￣2005年7月在我院进行肾活检的15例老年(年龄≥60岁)糖尿病患者合并的非糖尿病性肾病的临床表现和病理特点。结果:表现镜下血尿者4例,病理类型分别是IgA肾病、系膜增生性肾炎、膜增殖性肾炎和亚急性肾小管间质性肾病;肾病综合征者4例,病理类型分别是膜性肾病2例、系膜增生性肾炎和膜增殖性肾炎各1例;肾功能减退与糖尿病病史不相符者10例,占66.7%,表现为急性肾功能不全者7例,病理类型分别是慢性肾小管间质性肾病2例、系膜增生性肾炎2例、IgA肾病、膜增殖性肾炎和肾小球淀粉样变病各1例,表现为慢性肾功能不全者3例,病理类型均是慢性肾小管间质性肾病,伴有高血压性肾损害者8例。结论:老年糖尿病患者合并的非糖尿病性肾病,临床主要表现为与糖尿病病程不相符的肾功能减退,病理类型主要是慢性肾小管间质性肾病和系膜增生性肾炎,多数伴有高血压性肾损害。
To investigate the chnical and pathological characteristics of non-diabetic renal diseases （NDRD）in elder patients with type 2 diabetes mellitus.nethods： Fifteen patients（sixty years old or above）with type 2 diabetes mellitus who received renal biopsy from July 2000 to July 2005 were analyzed retrospectively. Results：Among all fifteen patients, four presented microhematuria and their pathological lesions were IgA nephropathy,mesangial proliferative glomerulonephritis （MsPGN）,membranoproliferative glomerulonephritis （MPGN）and subacute tubulointerstitial nephritis respectively;four presented nephrotic syndrome and two of them were membranous nephropathy. （MN）,one MsPGN and one MPGN;7 patients presented acute renal insufficiency and their pathological lesions were chronic tubulointerstitial nephropathy（TIN）in two,MsPGN in two,IgA nephropathy,MPGN and glomerular amyloidosis in one respectively;3 patients presented chronic renal insuiffciency were all TIN in pathological injuries.Eight subjects accompanied with hypertensive renal injuries, and two subjects accompanied with diabetic nephropathy.Conclusion：In the elder fifteen patients with NDRD, pathological lesions were mainly TIN and MsPGN for most of those whose clinical manifestation were renal insuffciency of NDRD.
出处
《中日友好医院学报》
2006年第3期133-136,共4页
Journal of China-Japan Friendship Hospital
关键词
非糖尿病性肾病
糖尿病
老年
病理
non-diabetic renal diseases
diabetes mellitus
elderly
pathology
