摘要
目的:探讨了银屑病患者血清HA、IL-2和TNF-α水平及意义。方法:应用放射免疫分析和ELISA对47例银屑病患者进行血清HA、IL-2和TNF-α检测,并与35名正常健康人作比较。结果:银屑病患者血清HA、IL-2和TNF-α水平非常显著地高于正常人组(P<0.01),而IL-2水平则显著地低于正常人组(P<0.01)。结论:检测银屑病患者血清HA、IL-2和TNF-α水平对其发病机理、了解病情、指导临床实践具有重要的临床价值。
Objective To investigate the changes of serum HA, IL - 2 and TNF - α contents in patients with psoriasis. Methods Serum HA, TNF - α levels were measured with RIA and IL - 2 levels was measured with ELISA in 47 patients with psoriasis as well as 35 controls. Results The serum HA, TNF - α levels were significantly higher in the patients than those in controls （P 〈 0. 01 ）, while the serum IL - 2 levels were significantly lower （ P 〈 0.01 ）. Conclusion Determination of serum HA, IL - 2 and TNF - α contents would be clinically useful for understanding the disturbances of immunomodulation in these patients.
出处
《放射免疫学杂志》
CAS
2006年第3期192-193,共2页
Journal of Radioimmanology
关键词
银屑病
透明质酸
白细胞介素-2
肿瘤坏死因子-Α
psoriasis, hyaluronic acid （ HA）, interleukin - 2 （ IL - 2） , tumor necrosis factor -α （ TNF -α）
