摘要
为探讨Graves病(GD)时外周血转化生长因子β1(TGFβ1)的变化及其意义。采用双抗体夹心ELISA法测定血清TGFβ1的水平,采用RIA法测定血清甲状腺激素水平。GD各组血清TGFβ1水平与对照组相比均显著增高(P<0.01),GD复发组血清TGFβ1水平低于GD未治疗组(P<0.05)。血清TGFβ1水平在GD时显著升高,其升高与甲状腺激素无关,而与GD自身免疫过程的活性有关。
To investigate the change of serum transforming growth factor-β1, （TGF-β1）, serum TGF-β1 was determined by ELISA, and the level of serum thyroid hormones was determined by RIA. The results showed that serum TGF-β1 increased significantly in untreated GD group compared with those in normal controls and recurrence group. From this study it can be conclu- ded that the increase of serum TGF-β1 in untreated GD group has no correlation with thyroid hormone, but has a correlation with autoimmune inflammatory process of GD.
出处
《标记免疫分析与临床》
CAS
2006年第2期81-82,共2页
Labeled Immunoassays and Clinical Medicine
