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新型抗肿瘤药物组蛋白去乙酰化酶抑制剂 被引量:12

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摘要 组蛋白去乙酰化酶抑制剂(HDACi)是一类新型的抗肿瘤药物,具有高效、低毒的特点, 其作用于肿瘤细胞后能够抑制肿瘤细胞增殖,诱导细胞周期阻滞,促进细胞分化或凋亡。目前该类药物已经在美国进入Ⅱ期临床研究。现综述HDACi的种类、生物学作用、抗肿瘤作用机制等的研究进展。
出处 《国际肿瘤学杂志》 CAS 2006年第6期404-406,共3页 Journal of International Oncology
基金 国家自然科学基金重点项目(30330620)
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