期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

微生物法生产1,3-丙二醇的基因工程研究进展 被引量：6

Recent progress of genetic engineering on 1,3-propanediol biosynthesis
下载PDF
导出
摘要 基因工程研究在生物法生产化工产品的过程中扮演着越来越重要的角色,对生物法生产1,3-丙二醇研究中利用基因工程手段对于菌体以及代谢途径进行改造的研究进行了考察,综述了其最新应用情况及其进展,并展望了未来的发展趋势。 Genetic engineering plays more and more important role in the current biochemical production process. The genetic thehniques related to the 1,3-propanediol biosynthesis system was surveyed, the propect of the recent developments in the field was addressed.
作者 黄志华 杜晨宇 王宝光 曹竹安
机构地区 清华大学化学工程系生物化工研究所
出处 《生物加工过程》 CAS CSCD 2006年第2期1-6,共6页 Chinese Journal of Bioprocess Engineering
基金 国家重点基础研究发展计划(973计划)(编号:2003CB716007)资助项目
关键词 1 3-丙二醇 基因工程 甘油脱水酶 辅酶NAD和NADH 1,3-propanediol genetic engineering glycerol dehydrogenase coenzyme NAD and NADH
分类号 Q93 [生物学—微生物学]
  • 相关文献

参考文献31

  • 1[1]Biebl H,Menzel K,Zeng AP,et al.Microbial production of 1,3-propanediol[J].Appl Microbiol Biotechnol,1999,52:289-297.
  • 2[2]Barbirato F,Himmi HE,Conte T,et al.1,3-propanrdiol production by fermentation:An intereting way to valorize glycerin from the ester and ethanol industries[J].Ind Crops Prod,1998,7:281-289.
  • 3[3]Saint-Amans S,Girbal L,Andrade J,et al.Regulation of carbon and electron flow in Clostridium butyricum VPI 3266 grown on glucoseglycerol mixtures[J].J Bacteriol,2001,183 (5):1748-1754.
  • 4[4]Homman T,Carmen T,Deckwer WD,et al.Fermentation of glycerol to 1,3-glycerol by Klebsiella and Citrobacter strains[J].Appl Microbiol Biotechnol,1990,33:121-126.
  • 5[5]Forage RG,Lin ECC.Dha system mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae[J].J Bateriol,1982,151(2):591-599.
  • 6[6]Zhu MY.Improved production of 1,3-propanediol in engineered E.coli by reducing accumulation of toxic intermediates:[D].USA:University of Wisconsin madision,1999.
  • 7[7]Toraya T,Fukui S.Diol dehydratase.In B12:Biochemistry and medicine[M].New York:NY John Wily & Sons,1982.
  • 8[8]Johnson EA,Lin ECC.Klebsiella pneumokniae 1,3-propanrdiol:NAD+ oxidoredutase[J].J Bateriol,1987,169:2050-2054.
  • 9[9]Johnson EA,Levine RL,Lin ECC.Inactivation of glycerol dehydrogenase of Klebsiella pneumoniae and the role of divalent cations[J].J Bacteriol,1985,164:479-483.
  • 10[10]Johnson EA,Burke SK,Forage RG,et al.Purification and properties of dihydroxyacetone kinase from Klebsiella pneumoniae[J].J Bacteriol,1984,160:55-60.

二级参考文献45

  • 1孙金凤,徐敏,张峰,王正祥.利用木糖和葡萄糖合成乙醇的新型重组大肠杆菌的研究[J].微生物学报,2004,44(5):600-604. 被引量：18
  • 2[1]Biebl H. Glycerol fermentation to 1,3-propanediol by Clostridium butyricum,measurement of product inhibition by use of a pH-auxostat. Appl Microbiol Biotechnol, 1991,35:701～705.
  • 3[2]Homann T, Tag C, Biebl H, et al. Fermentation of glycerol to 1,3-propanediol by Klebsiella and Citrobacter strains. Appl Micerobiol Biotechnol,1990,33:121～126.
  • 4[3]Biebl H, Marten S, Hippe H, et al. Glycerol conversion to 1,3-propanediol by newly isolated clostridia. Appl Microbiol Biotechnol,1992,36:592～597.
  • 5[4]Boenigk R, Bowien S, Gottschalk G. Fermentation of glycerol to 1,3-propanediol in continuous cultures of Citrobacter freundii. Appl Microbiol Biotechnol,1993,38:453～457.
  • 6[5]Zeng A N, Ross A, Biebl H, et al. Multiple product inhibition and growth modeling of Clostridium butyricum and Klebsiella pneumoniae in glycerol fermentation. Biotechnol Bioeng,1994,44:902～911.
  • 7[6]Fischer R J, Helms J, Durre P. Cloning, sequencing, and molecular analysis of the sol operon of Clostridium acetobutylicum, a chromosomal locus involved in solventogenesis. J Bacteriol,1993,175:6659～6669.
  • 8[7]Forage R G, Lin E C C. dha system mediating aerobic and anaerobic dissimilation of glycerol in Klebsiella pneumoniae NCIB 418. J Bacteriol,1982,151:591～599.
  • 9[8]Goodlove P E, Cunningham P R, Parker J,et al. Cloning and sequence analysis of the fermentative alcohol-dehydrogenase-encoding gene of Escherichia coli. Gene,1989,85:209～214.
  • 10[9]Johnson E A, Lin E C C. Klebsiella pneumoniae 1,3-Propanediol: NAD+-oxidoreductase. J Bacteriol, 1987,169:2050～2054

共引文献38

同被引文献58

引证文献6

二级引证文献10

生物加工过程
2006年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部