摘要
目的:探讨正常妊娠妇女妊娠各期血清碱性磷酸酶(ALP)值的变化规律并分析其参考值范围。方法:采用日本A u-640型全自动生化分析仪检测400例早、中、晚期妊娠妇女(实验组)及56名未孕健康育龄妇女的血清ALP值(对照组)。结果:对照组血清ALP值为(67.2±19.8)U/L,早期妊娠时ALP为(47.2±15.1)U/L,比对照组明显降低(P<0.01);中期妊娠时ALP值为(68.7±21.2)U/L,与对照组比较差异无显著性(P>0.05);晚期妊娠时ALP值为(156.8±52.3)U/L,比对照组比较显著升高(P<0.01)。血清ALP值随孕周的增加而上升。结论:正常妊娠时,孕妇体内ALP值在早孕时降低,中孕时无明显变化,晚孕时快速升高,建议建立晚孕期ALP参考值范围,以利于孕期保健。
Objective： To observe the serum alkaline phosphatase （ALP） level in normal pregnant women and analyze the normal level range in different gestationperiod. Methods： The serum level of ALP from 400 pregnant women in early, middle and late gestational period and 56 normal non-pregnant women as the control were measured with an Au-640 automatic biochemical analyzer according to the IFCC-recommended method. Results： The serum ALP level was （67.2±19. 8） U/L in the control, （47.2±15.1） U/L in the early gestational stage （lower than in the control, P〈0.01）, （68. 7±21.2） U/L in the middle gestatlonal stage （no significant difference from that in the control, P〈0.05） ,and （156.8± 52.3）U/L in the later gestational period （remarkably higher than in the control, P〈0. 01）. Conclusion： The serum ALP level may decrease during the early gestational stage, recover to the normal level during the middle gestational stage, and increase during the later gestational period, with which a set of the normal serum ALP level range can be set up to aid to monitor the health pregnancy.
出处
《广东医学院学报》
2006年第3期238-239,共2页
Journal of Guangdong Medical College
