摘要
本文探讨桥本氏病并发甲状腺癌的机理及发病关系。作者从1976年至1994年,手术治疗桥本氏病95例(均经病理检查证实),发现同时并存甲状腺癌6例(6.3%)。患者均为女性,平均年龄30.3岁;其中乳头状癌5例、滤泡状癌1例,2例并发甲状腺机能亢进。术前5例并发癌被漏诊或误诊,主要原因是癌灶较小,被肿大的甲状腺掩盖或医生对其缺乏认识。对3例作了根治手术,另3例仅作双侧甲状腺次全切除。术后随访1~17年,无癌复发或转移者。作者强调术中切片检查,根据病理类型进行手术。
Hashimoto’sdiseaseassociatedwiththyroidcancerisnotcommon.FromJanuary1976toDecember1994,atotalof95patientswithHashimoto’sdiseaseweretreatedsurgicaly.Six(5papil-lary1folicular)of95patientshadthyroidcancerwhichwasconcomitantlyrevealedpathologicaly.Theywerealwomenwithmeanageof30.3years.Thesizeoftumorwas0.3~2.0cm.Folow-upfor1~17yearsshowedthattheywerealaliveandhealthy.Twopatientsweremisdiagnosedashavinganaplasticcarcinomabutthedefinitivediagnosisbyimmunohistochemicalanalysiswasthyroidmalignantlym-phoma(B-celtype).Hashimoto’sdiseaseandthyroidcancerrelationship,diagnosis,andtreatmentarediscussed.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1996年第7期424-426,共3页
Chinese Journal of Surgery