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经皮电脉冲刺激治疗糖尿病神经原膀胱的疗效研究 被引量:3

Effects of External Electric Pulse Stimulating Vesica on Diabetic Neurogenic Bladder
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摘要 目的 观察经皮电脉冲刺激(EEPSV)对糖尿病神经原膀胱(DNB)患者膀胱残余尿(BRU)及白细胞排泄率(ULR)等的影响。方法 糖尿病(DM)患者在血糖控制后用B超检测其BRU,BRU≥50ml者(DNB患者)进入试验,根据DNB患者的BRU量分为轻(50~250m1)、中(251-450m1)、重(〉450ml或尿潴留)度DNB,对轻、中度DNB患者分别采用力合膀胱仪刺激治疗,40min/次,2次/d,共5d,或3次/d,共10d;对重度DNB患者则刺激治疗40min/次,4:,K/d,共15d,必要时加用α1-受体阻滞剂(高特灵1-2mg晚睡前),主要观察患者治疗前、后的血糖、血脂、肾功能、BRU、ULR及尿潴留等情况。结果 DNB患者经力合膀胱仪刺激治疗后血糖、血脂、尿酸代谢情况和肾功能无明显变化(P均〉0.05),BRU和ULR较治疗前明显减少(均P〈0.001),并发尿潴留的重度DNB患者能自行排尿,且消失的尿意恢复。结论 经皮电脉冲刺激阻断了DNB患者“梗阻-感染-尿潴留”的恶性循环,提高了DNB患者的生活质量和生存率,且无重大副作用。 Objective To investigate the effects of noninvasive external electric pulse stimulating vesica (EEPSV) on void bladder residue urine (BRU≥50 nd) and urine leukocyte excretion rate (ULR) of patients with diabetic neurogenic bladder (DNB). Methods DNB patients were defined as mild BRU (Bladder Residue Urine, 50 -250 ml), moderate BRU (251 - 450 ml), severe BRU ( 〉450 ml), the latter plus α1 -receptor blocker at a pinch. After 10 -30 days' treatment, we compared each patient's BRU, ULR, blood sugar and lipids with these before the treatment. Results After EEPSV treatment, there was no significant difference on metabolic amelioration in all patients ( P 〉 0. 05 ) ; but their BUR and ULR were all decreased significantly ( P 〈0. 01 ). In the severe DNB group, there was significant difference on the decline of BRU and ULR ( P 〈 0. 001 ), and the patients treated by EEPSV could micturate by theirselves. Conclusion EEPSV can improve DNB patients' vesical dysfunction.
出处 《中国全科医学》 CAS CSCD 2006年第14期1164-1165,共2页 Chinese General Practice
关键词 经皮电脉冲刺激 糖尿病 2型 膀胱 神经原 治疗 External electric pulse stimulating vesica Diabetes mellitus, type 2 Bladder, neurogenic Therapy
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