摘要
采用复凝聚法制备沙棘油微囊,用HPLC法测定微囊中维生素E的含量。结果表明,制品中沙棘油含量为30%,在0.1mol/L盐酸中维生素E约40min释放完全。在光照(4500lx)、高温(40、60、80℃,相对湿度均为75%)、高湿(相对湿度75%、90%)条件放置10d,碘价、过氧化值、酸价及皂化值基本不变,表明制品较稳定。
The microcapsules of oil of Hippophae Rhamnoides were prepared using complex coacervation. The content of vitamin E of the product was determined by HPLC. The results showed that the oil content was 30 %, and vitamin E was released completely in 40min in 0.1 mol/L HCI. The iodine value, peroxide value, acid value and saponification value of the product stored at 45001x, high temperature （40, 60 and 80℃, relative humidity 75 %） and high relative humidity （75 % and 90%） conditions respectively for 10d had no significant change.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2006年第7期474-475,共2页
Chinese Journal of Pharmaceuticals
关键词
沙棘油
复凝聚法
微囊化
溶出度
稳定性
oil of Hippophae Rhamnoides
complex coacervation
microencapsulation
dissolution
stability
