摘要
目的分析脑静脉血栓(CVT)病人的死亡原因。方法回顾分析136例CVT病人中5例死亡病例的病因、临床表现、影像学资料、治疗经过及死亡原因。结果病死率为3.7%。2例在急性期死亡,3例在慢性期死亡。直接死亡因素均为脑疝;间接死亡因素为颅内多发性出血和多个部位的脑静脉血栓形成,死亡组(3.20±0.84)支静脉受累,存活组(2.09±1.00)支静脉受累(P=0.016)。而性别、年龄、确诊时间、癫疒间发作、病灶部位及治疗前颅内压等没有显著增加死亡的危险性。某些临床表现,如失语、运动障碍、精神症状及意识障碍与死亡有关,但其系多发性颅内出血及多个部位脑静脉血栓所致。结论CVT病人的直接死亡原因为脑疝,间接原因为多发性脑静脉血栓和颅内多发性出血。死亡不仅可以发生在急性期,也可以出现在慢性期。
Objective To analyze the death causes of cerebral venous thrombosis （CVT）. Methods The etiologies, clinical characteristics, neuroimaging data, treatment courses and death causes of 5 out of 136 CVT patients were retrospectively analyzed. Results The fatality rate of 136 patients with CVT was 3.7%. Two patients died at the acute stage, and the other 3 during the follow-up period. The direct death factor was cerebral hernia. The indirect death factors were multiple cerebral hemorrhage and multiple CVTs （3.20±0.84 in death group vs. 2.09± 1.00 in survival group, P=0.016）. Sex, age, time of final diagnosis, epilepsy, location of the CVT, and pre-therapy ICP did not raise the risk rate of death. While the aphasis, paresis, mental disturbance and impaired consciousness due to the multiple cerebral hemorrhage and multiple CVTs, were related to the death. Conclusion The direct death cause of CVT was cerebral hernia, while the indirect causes were multiple cerebral hemorrhage and multiple CVTs. The death could happen both at acute stage and follow-up period.
出处
《中国微侵袭神经外科杂志》
CAS
2006年第7期300-302,共3页
Chinese Journal of Minimally Invasive Neurosurgery
关键词
窦血栓形成
颅内
死亡原因
sinus thrombosis, intracranial
cause of death
