摘要
目的:探讨阿托伐他汀对老年性脑梗死患者血清C-反应蛋白(CRP)水平的影响。方法:将70例脑梗死患者随机分为常规治疗组(35例)和阿托伐他汀治疗组(35例),30例健康人为对照组。阿托伐他汀治疗组于常规治疗基础上加用阿托伐他汀40 m g/d,疗程为15 d。两组均于治疗前和治疗结束时测定血清CRP。结果:阿托伐他汀组治疗2周后,CRP较治疗前下降(P<0.05)。常规组治疗前后无明显变化(P>0.05)。结论:在脑梗死早期给予大剂量阿托伐他汀治疗,使CRP水平下降,可能有利于抑制炎症反应、稳定斑块。
Objective：To explore the effect of atorvastation on serum C-reactive protein in patients with cerebral infarction. Methods：Seventy patients with cerebral infarction were randomly divided into routine therapy group （35 cases） and atorvastatin group （35 cases）. 30 healthy subjects were taken as control. In the atorvastatin group ,atorvastatin was given 40 mg/d. C-reactive protein （CRP） levels was measured before and after the treatments. Results ：After ratorvastatin treatment,the levels of CRP was decreased significantly （P〈0.01）. Conclusions ：Early atorvastatin treatment may be of great benefit to inhibit inflammatory responses,atherosderotic plaque stabilization in patients with cerebral infarction.
出处
《临床医药实践》
2006年第7期491-493,共3页
Proceeding of Clinical Medicine
关键词
阿托伐他汀
C-反应蛋白
脑梗死
atorvastatin
C-reactive protein
cerebral infarction
