摘要
目的:研究黄芪肠内营养对2型糖尿病合并缺血性卒中病人体液免疫(IgA、IgG、IgM)和细胞免疫(T细胞亚群)的影响。方法:将64例病人随机分为治疗组和对照组,每组32例。治疗组给予黄芪水煎液(相当于生药60 g)加改良匀浆膳;对照组给予能全力,共30 d。两组肠内营养支持前后均测定IgA、IgG、IgM和T细胞亚群,同时监测空腹血糖、血浆清蛋白、转铁蛋白和血红蛋白等营养指标。结果:①治疗组肠内营养支持后,IgG、IgM、CD4和CD4/CD8比值均升高,与对照组比较,差异有显著性意义(P<0.05,P<0.01);②治疗组肠内营养支持后空腹血糖降低,与对照组比较,差异有显著性意义(P<0.01)。③两组病人经营养支持后,转铁蛋白升高(P<0.05)。结论:黄芪肠内营养可明显改善2型糖尿病合并缺血性卒中病人免疫功能及空腹血糖。
Objectives：To study the effect of Astragalus-supplemented enteral nutrition on the humoral immunity（IgA,IgG,IgM） , ceUular immunity （T-lymphocyte subsets） in type-2 diabetic patients with ischemic stroke. Methods ：64 cases of type-2 diabetic patients with ischemic stroke were randomly divided into treated group and control group. The treated group was treated with homogenized diet and Radix Astragalis（ equivalent to 60g crude drug）, and the control group was treated with Nutrison fibre. Venous blood from cubital vein was collected before and after treatment to detect the IgA,IgG,IgM, T-lymphocyte subsets,fasting blood glucose,serum proteins and the nutritional status was evaluated. Results： Compared with the control group, IgG ,IgM, CD4（ % ） ,CD4/CD8 ratio in the treated group increased significantly（ P 〈 0.05, P 〈 0.01 ） ;fasting blood glucose in the treated group was significantly improved （P 〈 0.01 ）. During the period of this study, the levels of serum proteins had no significant changes between two groups. Conclusions：Astragalus-supplemented enteral nutrition can improve the immune function and fasting blood glucose of type-2 diabetic patients with ischemic stroke.
出处
《肠外与肠内营养》
CAS
2006年第4期206-208,共3页
Parenteral & Enteral Nutrition
关键词
2型糖尿病
缺血性卒中
黄芪
肠内营养
免疫功能
Diabetes Mellitus, Type 2
Ischemic stroke
Radix Astragalis
Enteral nutrition
Immune function
