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前哨淋巴结检测在子宫颈癌根治术中的应用

Apply value of sentinel lymph node detection in patients with cervical cancer
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摘要 目的探讨前哨淋巴结(SLN)检测对子宫颈癌根治的临床价值。方法应用蓝染料法对33例子宫颈癌患者在根治术中于宫颈肿瘤周围的正常组织3、6、9、12点处注入美蓝或专利蓝溶液4ml识别和定位蓝染的淋巴结,然后行盆腔淋巴清扫术并送病检。结果33例宫颈癌患者中1例宫颈淋巴管无染料摄取;淋巴管有蓝色染料摄取者32例,其中26例成功识别SLN,识别率为81.25%(26/32);7例识别SLN失败,失败率为21.88%(7/32)。26例成功识别SLN的患者中6例(23.08%)患者发现盆腔淋巴结转移,共12枚转移淋巴结均为SLN,敏感性为6/6,准确性为100%(26/26),假阴性率为0。结论应用蓝染料法SLN检测具有较高的临床应用价值。 Objective To probe into the clinical apply value of sentinel lymph node detection in patients with cervical cancer. Methods 33 patients with cervical cancer underwent SLNS detection by using blue dye or methlene blue 4ml or lymphasurin was injected into the cervix at 4 points around the tumor at the time of radical hysterectomy and bilateral pelvic lymphadeneetomyl tumor characteristics surgical findings and specific locations of lymphatic dye uptake were recorded and correlated with final pathology results. Results Among 33 patients undergone this detec- tion, dye uptake was not seen in 1 patient, dye uptake was seen in 32 patients, the SLNS were successfully detected in 81.25% (26/32);7 patients didn't discriminated SLN, the rate was 21.88 % (7/32). There were 6 cases who were discovered pelvic cavity lymph nodes metastases in 26 patients discriminated SLN successfully, in all 12 piece metastases lymph nodes were SLN, sensitivity was 6/6, accuracy was 100 % (26/26), fake negative rate was 0. Conclusion Sentinel lymph node dectection by the way of blue dye has more clinical apply value in patients with cervical cancer.
出处 《中国基层医药》 CAS 2006年第6期933-934,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 宫颈肿瘤 淋巴结 妇科外科手术 Cervical neoplasms Lymph Gynecologic surgical procedures
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