摘要
目的建立测定止咳糖浆中盐酸麻黄碱的含量测定方法。方法采用高效液相色谱C18柱，流动相为乙腈-0．1％磷酸（5：95），流速为1.0ml／min，检测波长办206nm。结果盐酸麻黄碱在32~160μg范围内有良好的相关性，r＝0-9999，回收率为98．99％，RSD为0．9％（n=6）。结论该法简便，专属性强。
Objective To establisb method for determining ephedrine hydrochoride in Zhiketangjiang by RP-HPLC. Methods The Agilent Extend C18 column with acetonitrile -0.1% H3PO,（5： 95） as the mobile phase was used. The flow rate at 1.0 ml/min and the detective wavelength was at 206 nm. Results The calibration curve was linear at a range of 0.020 28 -1. 011 04 μg for the ephedrine hydrochloride （r = 0.999 9）. The average recovery was 97.69% and RSD was 0.9% （ n = 6）. Conclusion The method is accurate with a good reproducibility and can be used as a quantitative analysis for this preparation.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2006年第7期1367-1368,共2页
Lishizhen Medicine and Materia Medica Research
