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血清胱抑素水平在肝硬化、肿瘤及肾病患者检测中的临床意义 被引量：4

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摘要 目的探讨血清胱抑素水平在评价肝硬化、肿瘤及肾病患者中肾功能损害程度的应用价值。方法选择30例健康对照者,50例肝硬化、46例肿瘤、56例肾脏疾病患者,同时标本采样检测患者血清胱抑素C(cystatin C)浓度、血尿素氮(BUN)和血肌酐(Scr)值,计算内生肌酐清除率(Ccr)。结果在肝硬化、肿瘤和肾病患者中,血清胱抑素C浓度与Ccr成负相关关系(r分别为-0.62、-0.74、-0.71,P均<0.01),且BUN、Scr、cystatin C均比对照组高,Ccr比对照组低(P均<0.01)。结论血清胱抑素水平能作为肝硬化、肿瘤及肾病患者疾病发展过程中肾功能损害的检测指标,对反映肾功能状况有应用价值。
作者 王贵生
机构地区 广西柳州市工人医院广西医科大学第四附属医院检验科
出处 《右江民族医学院学报》 2006年第4期565-566,共2页 Journal of Youjiang Medical University for Nationalities
关键词 血清 西司他汀类 肝硬化 肿瘤 肾疾病 肾功能损伤
分类号 R730.3 [医药卫生—肿瘤]
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参考文献7

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二级参考文献12

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共引文献35

同被引文献37

引证文献4

二级引证文献7

右江民族医学院学报
2006年 第4期

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