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胸腺切除治疗重症肌无力的疗效分析 被引量:12

Effect of thymectomy in treatment of myasthenia gravis: analysis of 67 cases
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摘要 目的评价67例重症肌无力患者胸腺切除术的治疗效果。方法回顾性分析我院1995年12月至2004年12月期间对67例行胸腺切除术的重症肌无力患者的临床资料,对其临床特点、手术方式、围手术期处理和治疗效果进行了探讨。结果按Monden标准评价疗效:缓解22例(32.8%),改善26例(38.8%),无变化14例(20.9%),恶化5例(7.5%),总有效率为71.6%。结论胸腺切除术治疗重症肌无力疗效可靠,对MG患者应积极行胸腺切除术。 Objective To evaluate the clinical effects of thymectomy in treatment of myasthenia gravis : (MG). Methods The clinical data of 67 patients, 29 males and 38 females, aged 10.5 ~ 68, who underwent thymectomy were analyzed. Results According to the Monden's standard the overall effective rate of thymectomy was 71.6%. The remission rate was 32.8% (22/6), the improvement rate was 38.8% (26/67), 14 patients showed no change (20.9%), and deterioration was seen in 5 patients (7.5%). Conclusion An effective method to treat MG, thymectomy should be performed on most of the MG patients early and actively.
出处 《中华医学杂志》 CAS CSCD 北大核心 2006年第28期1978-1980,共3页 National Medical Journal of China
关键词 重症肌无力 胸腺切除术 Myasthenia gravis Thymectomy
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参考文献8

  • 1张其刚,谭胜,童向东,白德威.应用定量评分分析重症肌无力患者术后疗效及其影响因素[J].中华医学杂志,2005,85(30):2144-2145. 被引量:7
  • 2范志民,闻国强,张振和,刘国津.胸腺切除术在治疗重症肌无力中的价值[J].中华医学杂志,1998,78(5):363-365. 被引量:11
  • 3Nieto PI, Roblel PPJ, Pajulo CM, et al. Prognostic factors for myasthenia gravis treated by thymectomy: review of 61 cases. Ann Thorac Surg, 1999, 67:1568-1571.
  • 4Roberts PF, Venuta F, Rendina E, et al. Thymctomy in the treatment of ocular myasthenia gravis. J Thorac Cardiovasc Surg,2001, 122:562-568.
  • 5Essa M, Medany Y, Hajjar W, et al. Maximal thymectomy in children with myasthenia gravis. Eur J Cardiothorac Surg, 2003,24:187 -189.
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  • 8Mussi A, Lucchi M, Murri L, et al. Extended thymectomy in myasthenia gravis: a team-work of neurologist, thoracic surgeon and anaesthesist may improve the outcome. Eur J Cardiothorac Surg,2001, 19:570-575.

二级参考文献5

  • 1Alfred J HI, Richard JB, Raina ME, et aL Myasthenia gravis:recommendation for clinical research. Ann Thorac slug, 2000, 70:327 -334.
  • 2Osserman KE, C, enkins G. Studies in myasthenia gravis: review of a twenty-year experience in over 1200 patients. Mount Sinai Hospital J Med, 1971, 38:497-504.
  • 3Masaoka A, Monden Y, Nakahara K, et al. Follow-up study of thymomas with special, reference to their clinical stages. Cancer,1981, 48:2485-2492.
  • 4Nieto PI, Roblel PPJ, Pajulo CM, et al. Prognostic factors for myasthenia gravis treated by thymectomy: review of 61 cases. Ann Thorac surg, 1999, 67 : 1568-1571.
  • 5范志民,闻国强,张振和,刘国津.胸腺切除术在治疗重症肌无力中的价值[J].中华医学杂志,1998,78(5):363-365. 被引量:11

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